Technical Assistant I - Ii Cheeseman Lab

TITLE: Technical Assistant I/II (Large Scale Cell Biology)

Classification: Exempt: Research Staff

REPORTS TO: Principal Investigator or other supervisory lab personnel

All experience levels are encouraged to apply!

PROJECT SUMMARY

Analyzing Cell Biology at Scale

The Cheeseman lab is seeking an enthusiastic and motivated individual with boundless curiosity who is interested in conducting research to probe the inner workings of human cells. The work in the Cheeseman lab is focused on understanding core cell biological questions, including applying fluorescence microscopy and functional genetic strategies to define the requirements for cell division and other cellular processes. Our recent work conducted pooled cell biological profiling using Cas9-based gene targeting for the ~5,000 essential genes in human cells acquiring microscopy-based images for millions of cells. We are recruiting a researcher to contribute to these large scale cell biology efforts to extend this approach to diverse cell biological markers, cell lines, and different cell states unlocking fundamental new biological discoveries. This collaborative project and our dynamic environment provide strong opportunities for training, growth, and professional development.

OVERALL RESPONSIBILITY

Designs and performs bench level experiments and independent research projects (related to large scale cell biology, optical pooled screening, and targeted cell biological experimentation) to support scientific research objectives of a lab or group. Analyzes experimental data, addresses methodological problems in experimental protocols and results, reports data to supervisor, and presents results. Conducts laboratory tasks and organization to ensure the smooth operation of the group. Uses discretion in prioritizing and organizing workflow and in optimizing methodologies and results. Contributes to lab organization and operation.

CHARACTERISTIC DUTIES

· In consultation with the Principal Investigator or other project manager, designs and conducts bench level experiments and small independent research projects.

· Independently operates lab equipment and prepares and orders necessary supply stocks. May work with vendors to address equipment, reagent, or supply issues.

· Performs analysis of experimental results by identifying methodological problems and helping to identify and implement modifications in research protocols.

· Documents, compiles, and assists in interpreting experimental data. Reports data to supervisor in oral and written reports.

· Assists with determining the order of research processes that best supports essential project goals.

· Operate and maintain laboratory equipment to complete investigations.

· Organize laboratory reagent collections, including facilitating the distribution of research materials to other labs.

· May forecast materials and supply needs for the lab as a whole, orders basic lab supplies, and assists the Purchasing department with servicing and maintaining major lab equipment.

· May interact with vendors to investigate novel supplies and technology.

· Give presentations on research findings, including lab meeting and institute-wide meetings.

· Consult the scientific literature as needed.

· Other tasks as required or assigned.

QUALIFICATIONS

All experience levels are encouraged to apply!

· Bachelor's degree in biology or a field directly related to the work.

· Must have 1+ years of experience working in a research laboratory.

· A background in molecular biology or cell biology is desired, including microscopy-based approaches.

· Proficient in basic lab techniques and principles of molecular biology required.

· Knowledge of various scientific databases and publications preferred.

· Experience with computer programming and database management a plus.

· Excellent written and oral communication skills, strong organizational skills required.