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SalaryFate Therapeutics is seeking a highly motivated stem cell biologist to join our Process Development team to support the development of novel cell immunotherapies. This position will be responsible for supporting development of next-generation platforms, including iPSC maintenance and expansion, in vitro differentiation of iPSCs towards hematopoietic lineages, and process characterization. Candidates must have robust cell culture experience, and an understanding of stem cell biology, the hematopoietic system, and immunology is preferred. This position will require independent research and coordination with the Process Development group. This is a temporary full-time position and is located at our corporate headquarters in San Diego, CA.
Responsibilities
- Design, execute, and analyze experiments to develop and refine the parameters for iPSC expansion, iCD34 differentiation, and iT differentiation for iPSC-derived T cell product manufacturing with the guidance of the hiring manager.
- Perform assessment of cell cultures, maintenance of iPSCs, hematopoietic differentiations, and T cell differentiations.
- Perform characterization of stage-specific process utilizing flow cytometry, gene expressing profiling, and media analysis.
- Collect, organize, and analyze data in a timely manner and in accordance with company policy.
- Reagent management and aseptic preparation of reagent stocks including media, cytokines, & small molecules.
- Communication of culture assessments, results, and reagent inventories in a timely manner to relevant team members.
Qualifications
- B.S. / M.S. with a minimum of 4 years of relevant experience in cell culture techniques.
- Hands-on experience with human ES/iPSC culture is preferred.
- Working knowledge of stem cell biology, immune system and/or developmental hematopoiesis is preferred.
- In-depth experience with multi-color flow cytometry data acquisition and manual analysis using FlowJo, or similar.
- Proficient with office and statistics software, such as Prism.
- Strong attention to detail, analytical, time management, organizational and interpersonal skills.
- Meticulous record-keeping skills and excellent communication skills are a must.
- Comfortable in adjusting workload based upon adjustment of priorities.
- Prior Process Development experience is a plus.
- Positive outlook, willingness to lean and test new ideas, and desire to work collaboratively in a team environment.
Working Conditions and Physical Requirements
- Will require working with cells and cell lines of human and/or animal origin.
- Will require working with hazardous materials.
- Occasional weekend work will be required.
- Ability to lift up to 10 lbs.
$48 - $53 an hour
The preceding job description indicates the general nature and level of work performed by employees within this classification. Additional and incidental duties related to the primary duties may be required from time to time.
Equal Employment Opportunity
Fate Therapeutics, Inc. is an equal opportunity employer. We value diversity and are committed to creating an inclusive environment for all employees.
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About Fate Therapeutics, Inc.
Fate Therapeutics is a clinical-stage biopharmaceutical company dedicated to bringing a first-in-class pipeline of induced pluripotent stem cell (iPSC)-derived cellular immunotherapies to patients with cancer and autoimmune diseases. Using its proprietary iPSC product platform, the Company has established a leadership position in creating multiplexed-engineered iPSC lines and in the manufacture and clinical development of off-the-shelf, iPSC-derived cell products. The Company’s effector cell pipeline includes multiplexed-engineered, iPSC-derived natural killer (NK) cell and T-cell product candidates, which incorporate novel synthetic controls of cell function, such as chimeric antigen receptors (CARs) to target tumor-associated antigens and are intended to deliver multiple mechanisms of therapeutic importance to patients including in combination with well-established cancer therapies. Fate Therapeutics is headquartered in San Diego, CA. For more information, please visit www.fatetherapeutics.com.
