The Immunology group in Translational Medicine at Genentech is seeking a highly talented, driven and motivated lab-based Scientist to support our research and clinical development activities in gastrointestinal and fibrotic diseases. Our department is responsible for defining biomarker and personalized healthcare strategies in our clinical trials, and interpreting biomarker results to support biological rationale and decision making. Through our clinical trials, as well as our translational research efforts, our group identifies and implements biomarkers to evaluate disease heterogeneity, target-engagement, mechanism of action, and disease modification.
The successful candidate will be expected to work independently and collaboratively on pipeline projects and disease area activities to support clinical development, providing both scientific and technical expertise and generating solid data. Excellent communication skills, will facilitate fruitful and open collaborations with other functions including Research, Bioanalytical Assay Science, Diagnostics, Clinical Pharmacology, Biostatistics and Bioinformatics. The successful candidate will be expected to present their work to the department, cross-functional teams, internal review committees and external conferences.
Responsibilities
- Discover and evaluate candidate biomarkers
- Develop and implement biomarker assays in preclinical models and clinical trials
- Evaluate new technologies as potential novel biomarker assay platforms
- Analyze large data sets using available analysis tools
- Documents experiments and studies in lab notebook
- Communicates findings to their scientist/manager
- Coordinates interdepartmental and external collaborations
- Perform other duties as assigned
Strong candidates for this position will meet most of the following requirements:
- BS and/or MS in pharmacology, immunology, molecular biology, biochemistry or related field.
- At least 3 years of relevant experience in inflammation and/or fibrotic disease research
- Familiarity with a broad spectrum of laboratory techniques, such as cell culture, ELISA, qPCR, cytokine profiling, LC/MS, flow cytometry, NGS, and human whole blood assays
- Experience with analysis of data from genomic sequencing, scRNA-seq, TCR-seq, CITE-seq or spatial transcriptomics is a plus.
- Able to Independently design, execute and interpret experiments.
- Have excellent communication and time management skills and be willing to work in a collaborative environment.
- Can present their research clearly and effectively.
The expected salary range for this position based on the primary location of California is $100,000- $185,600. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Who we are
A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work.
Diversity and Inclusion (D&I) are critical to the success of our company and our impact on society. We believe that by championing diversity of background, thought and experience, we can foster a sense of belonging and provide an environment where every employee feels valued, included, and able to contribute their best for the patients we serve. We're focused on attracting, retaining, developing and advancing our people to their full potential by rewarding bold ways of thinking and integrating inclusive behaviors into every aspect of our work.
Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status. For more information about equal employment opportunity, visit our Genentech Careers Homepage.
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