Address
Form of workGenetics-423501
Career Area :Research Professionals
Posting Open Date:01/24/2024
Application Deadline:02/16/2024
Open Until Filled:No
Position Type:Permanent Staff (EHRA NF)
Working Title:Research Specialist (ADV) Mohlke Lab
Appointment Type:EHRA Non-Faculty
Position Number:20054329
Vacancy ID:NF0007748
Full Time/Part Time:Full-Time Permanent
FTE:1
Hours per week:40
Position Location:North Carolina, US
Hiring Range:$61,458 - $80,000
Proposed Start Date:03/04/2024
Be a Tar Heel!:A global higher education leader in innovative teaching, research and public service, the University of North Carolina at Chapel Hill consistently ranks as one of the nation’s top public universities. Known for its beautiful campus, world-class medical care, commitment to the arts and top athletic programs, Carolina is an ideal place to teach, work and learn.One of the best college towns and best places to live in the United States, Chapel Hill has diverse social, cultural, recreation and professional opportunities that span the campus and community.University employees can choose from a wide range of professional training opportunities for career growth, skill development and lifelong learning and enjoy exclusive perks for numerous retail, restaurant and performing arts discounts, savings on local child care centers and special rates on select campus events. UNC-Chapel Hill offers full-time employees a comprehensive benefits package, paid leave, and a variety of health, life and retirement plans and additional programs that support a healthy work/life balance.
Primary Purpose of Organizational Unit:The mission of the Genetics department is to provide basic and applied genetic/genomic research, education, and training at the interface between biology, chemistry, physics, computer science, mathematics, the social sciences, public health, and medicine to have a profound effect on how medicine will be practiced in the future.
Our graduate programs train students to be creative, sophisticated research scientists prepared to pursue careers focused on genetics and genomics working in academic science, government, or commercial positions. Students conduct their dissertation research using diverse experimental approaches – from classical genetics to the most modern molecular methods – to address a broad range of contemporary problems in biomedical science.
The Department also includes a clinical arm focused on medical genetics, which covers the broad spectrum of clinical genetic research from disease prevention to diagnosis and treatment. This specialty includes evaluation, mutation discovery, counseling and risk assessment through analysis and genetic testing. Locating the clinical group alongside basic scientists facilitates integration of cutting-edge genetic research with patient care.
The primary purpose of this position is to serve as Research Specialist and laboratory manager in the laboratory of Dr. Karen Mohlke. This laboratory studies human genetic susceptibility to type 2 diabetes, obesity, dyslipidemia, and related quantitative traits. The Research Specialist will perform research using molecular and cellular biology approaches to test the molecular and biological consequences of human genetic variants associated with common, complex metabolic traits. The Research Specialist will be responsible for maintenance of a safe and efficient laboratory environment, including updating the lab safety plan and ensuring that lab members are safely trained in new procedures. The Research Specialist will maintain laboratory resources, including supplies, chemicals, equipment, and facilities and identify new supplies and equipment to increase efficiency of lab activities. The selected candidate will work with lab members and collaborators and train other researchers, including technical staff, postdoctoral fellows, graduate students, undergraduate students and others. Research activities will include molecular genetic assays and analyses such as PCR, cloning using bacterial and viral vectors, mutagenesis, measurement of RNA and protein levels, mammalian cell culture, tissue processing, sequencing library preparation, chromatin analysis, basic statistical analyses, and bioinformatic analyses using human genome resources. The Research Specialist will develop and improve CRISPR-based genome editing methods in the laboratory, including prime editing and implementation of multi-plexed high-throughput genome editing screens and assays.
Minimum Education and Experience Requirements:Bachelor’s degree in a discipline related to the area of assignment; or equivalent combination of training and experience. All degrees must be received from appropriately accredited institutions.
Required Qualifications, Competencies, and Experience:* Candidate must be adept at standard molecular biology techniques and tissue culture.
* Candidate must have knowledge of human genetics concepts.
* B.S. in Genetics, Cell and Molecular biology, or a related field
* Eight years experience in a research laboratory using standard molecular biology techniques and tissue culture
* Ability to use the research literature to design detailed experimental methods, procedures, and/or techniques
Not Applicable.
