Dr. Jinghui Zhang, Member, in the Department of Computational Biology, is searching for a highly motivated candidate inspired to pursue cutting-edge research involving using long-read sequencing technology to advance pediatric cancer research. Under the supervision of Dr. Zhang, a world leader of methods development and cancer genomics, the candidate will be developing and applying new analytical approaches to study complex genomic architecture, genetic predisposition and treatment resistance using long-read sequencing data. The candidate will have the opportunity to lead key research projects, serve as a project manager in multi-disciplinary collaboration, participate in mentoring and training, and lead manuscript preparation. The research areas involve complex re-arrangements, transcription regulation, tumor heterogeneity, non-coding variants, haplotype phasing.
The successful candidate shall have excellent training and experience in high-throughput genomic data analysis including the use of long-read sequencing data. Additional training and experience in genetic variation, epigenetics and cancer genomics are highly desired. The candidate is expected to be a critical thinker, can perform high-level research with minimum supervision, and capable of implementing novel computational methods for solving complex problems. The candidate must have an excellent publication record and great presentation and communication skills. Experience in mentoring and project management is highly desirable.
Recognized as a world leader of genomic research and an elected Fellow of the International Society for Computational Biology (ISCB), Dr. Zhang has led high-impact research in the development and application of innovative computational methods, discovering novel targets and accelerating research and genomic data sharing to advance the diagnosis, treatment and surveillance of pediatric cancers and survivors. The Zhang lab has a great track record in mentoring and training as 11 former postdoctoral fellows or staff members now hold independent faculty positions and 3 are in leadership positions in industry.
St. Jude provides a highly interactive and supportive environment for researchers’ career development.
Job Responsibilities:
Lead computationally focused scientific research projects with minimal supervision from their PI.
Develop Computational Research strategies including new technologies and methods in partnership with Principal Investigators.
Manage large-scale, multidisciplinary projects through proactive research collaboration, and provide direction in specific area of expertise.
Design and conduct high-quality Computational Research.
Analyze emerging trends and technical advances, generate new research concepts and procedures, and lead adoption.
Oversee collection and management of data, data analysis, and interpretation of results/findings for laboratory projects to translate research discoveries into meaningful changes in scientific and clinical practices.
Publish as first author or co-author for complex projects or in high-impact interdisciplinary journals; provide peer review guidance as a member of an editor board (as applicable).
Present insights as an expert at external meetings and conferences.
Serve as a mentor and provide coaching and guidance to research staff.
Perform other duties as assigned to meet the goals and objectives of the department and institution.
Maintains regular and predictable attendance.
Minimum Education and/or Training:
Bachelor's in Bioinformatics, Molecular Biology, Biochemistry, Computer Science, or related field.
Master's degree or PhD preferred.
Minimum Experience:
Minimum Requirement: Bachelor's degree and 13+ years of relevant experience.
Experience Exception: Master's degree and 11+ years or relevant experience (OR) PhD with 8+ years of relevant experience.
Rough criteria for this position based on publication output: 5-6 first author papers IF > 10 (or equivalent contribution to other research outputs).
Experience directing multiple complex research studies from end to end in a technical capacity.
Proven experience in driving results indirectly through a team of researchers.
Experience training and guiding early-career researchers.
Proven performance in earlier role/comparable role
Compensation
In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $138,320 - $262,080 per year for the role of Principal Computational Research Scientist - Zhang Lab.Explore our exceptional benefits!
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Today, we continue the mission to advance cures and means of prevention for pediatric catastrophic diseases through research and treatment. As we accelerate this progress globally, we believe our legacy of diversity, equity and inclusion is foundational to success. With the commitment of leaders at all levels of the organization, we strive to ensure the St. Jude culture, leadership approaches and talent processes are equitable and culturally responsive. View our Diversity, Equity and Inclusion Report to learn about the hospital’s roots in diversity, equity and inclusion, where we are today and our aspirations for an even better future.
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