Laboratory Assistant

Parvus Therapeutics Inc.

Parvus Therapeutics Inc. is a privately held biopharmaceutical company developing Navacims™, a platform technology based on foundational research published in 2016 (Nature 530:434), to treat autoimmune diseases. Parvus’ mission is to shift the treatment paradigm toward Navacim™-directed immune regulation, avoiding non-specific immune suppression associated with current therapies. Parvus’ innovative approach has the potential to benefit millions of patients suffering from debilitating autoimmune diseases and other chronic inflammatory conditions. Parvus is advancing a pipeline of proprietary drug candidates for multiple autoimmune indications through preclinical development and into the clinic. Parvus’ leadership team is experienced in successful drug discovery, development, manufacturing, regulatory approval, and commercialization.

About Navacims™

Navacims™ are a novel first-in-class nanomedicine designed to treat autoimmune disease by selectively modulating disease-specific cellular responses without impairing normal immunity. Navacims™ specifically target and act only on disease causing effector T cells, delivering a signal that programs effector T cells to differentiate into regulatory T (Treg) cells specific for self-antigens relevant to the patient’s disease. These disease- or tissue-specific Treg cells induce immunological tolerance to block undesired immune responses to self-antigens, while maintaining normal immune surveillance and activity.

The Position

Parvus is seeking a Laboratory Assistant who will be responsible for maintaining a safe and organized laboratory. The primary duties include ensuring the laboratory is clean and well-stocked, assisting the laboratory staff with experiments, equipment maintenance, and experimental setup, as well as following all safety protocols and procedures to maintain a secure working environment. The successful candidate will have a science background, possess strong attention to detail, and exhibit excellent organizational skills. This role provides an exceptional opportunity to gain valuable laboratory experience while contributing to innovative research.

Primary Responsibilities:

• Setting up laboratory equipment and instruments for experiments or tests.
• Preparing buffers and reagents to support Chemistry and Bioassay Analytical Development groups.
• Supporting analytical method development, cell culture, and process development sample testing.
• Collaborating with researchers, scientists, and other team members to support ongoing projects. Communicating effectively to provide updates on progress and address any issues.
• Preparing and handling various types of samples, such as rodents, biological specimens, chemicals, or materials, for experimentation and analysis. Following established protocols and procedures to ensure accuracy and consistency in sample preparation.
• Assisting in the collection of data during experiments or tests. Recording and documenting experimental procedures, observations, and results accurately.
• Assisting in identifying and resolving technical issues or challenges that may arise during experiments or tests.
• Keeping detailed records of experiments, procedures, and results. Compiling data and contributing to the preparation of reports or publications.
• Responding to facility alarms for monitored devices within the laboratories (such as freezers, refrigerators, or incubators), including instances that occur over the weekend or holidays.
• Overseeing the vendor-managed inventory (VMI) program.
• Managing general organizing of the laboratory and maintaining inventory repositories and supplies to ensure smooth laboratory operations.
• Managing outbound and inbound shipments for the team, including shipment of hazardous materials following Department of Transportation regulations.
• Performing regular (weekly and monthly) equipment cleaning and sterilization (including aseptic and non-aseptic equipment).
• Monitor Analytical gases and cryogenic liquids levels and ensure continuous supply via ordering system.
• Performing and make arrangements for maintenance and calibration of laboratory equipment to ensure accuracy and reliability.
• Maintain a hazardous material inventory.
• Properly handle and dispose of waste.
• Support safety protocols and guidelines to promote a safe work environment.

Requirements:

• Bachelors degree, or equivalent experience in Biology, Chemistry or Physics
• At least one year of relevant experience in an academic lab (classes not included) or biotechnology work experience preferred
• Computer/IT literacy, including competency with word-processing and spreadsheet programs, for database/master file setup and maintenance
• Familiarity with laboratory equipment and techniques
• Knowledge of safety protocols and procedures
• Ability to work in a fast-paced environment and adapt to changes under short notice with a proactive attitude
• Organized and detail oriented, possessing excellent record-keeping skills
• Good communication and teamwork skills
• Ability to lift up to 25 lbs without assistance

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