TEMP Scientist I, Analytical & Formulation Development

Headquarters Location: South San Francisco, CA

Candidate Location: Hybrid

Travel Required: 5%

Reports To: Sr. Scientist I, Process Sciences, AFD

Department: Analytical & Formulation Development

Position Type: Temporary (6 months), Non-Exempt

About CytomX Therapeutics:

CytomX Therapeutics, Inc. is committed to changing the treatment of cancer with our novel Probody therapeutic platform. Our commitment to transforming lives with safer, more effective therapies is driven by our curiosity and passion for innovation and our belief that by acting with integrity in an honest, respectful, ethical manner, we have the power to change lives. Our workplace embodies collaboration, open communication, celebrating our successes, and holding each other to the highest possible standards. CytomX has a broad pipeline, which comprises seven therapeutic candidates across multiple treatment modalities including antibody-drug conjugates ("ADCs"), T-cell engaging bispecific antibodies ("TCBs"), and immune modulators such as cytokines and checkpoint inhibitors ("CPIs"). Learn more atwww.cytomX.com.

Who You Are and What You'll Do:

You are passionate about life sciences and making a difference to cancer patients, their families, and healthcare providers. This position requires the candidate to have the ability to support protein analytics and characterization needs for discovery and development programs at CytomX Therapeutics. The position will provide analytical support to upstream and downstream process development and Formulation Development in the analysis of in-process and final product samples. The position will also execute and develop HPLC and gel-based analytical methods for in-depth protein characterization. As such, working knowledge of some of the analytical methods, such as: LC, CE-SDS, icIEF, and/or mass spectrometry-based assays is important. Experience in binding and cell-based assay development is a plus. The individual will be required to diligently document experimental work in electronic lab notebooks and will be required to write (or may contribute to writing) SOPs and reports.

Job Responsibilities:

• Development and execution of analytical methods for complex protein therapeutic candidates such as HPLC (SEC, RP-HPLC, ion exchange, etc.), capillary electrophoresis, Mass spectrometry-based assays such as LC-MS, ELISA-based analytical methods for protein/antibody characterization, based on the needs.
• Apply scientific principles, current technologies, and personal experience to support design and execute of appropriate experiments to solve problems.
• Support the development of SOPs for various analytical methods and the qualification of methods required for technical transfer to CMO/CRO facilities.
• Maintain and troubleshoot the analytical instrumentation as required.
• Support troubleshooting of assay performance as needed.
• Analyzing samples for stability studies
• Working in a regulated environment and authoring /reviewing laboratory investigations.
• Document experimental work in electronic lab notebooks, SOPs and reports.
• Communicate results and propose scientifically based recommendations.

Minimum Qualifications:

• PhD with 1+ year(s) of industry experience, or
• Master of Science (MS) degree with 5+ years of industry experience, or
• BS with 8+ years of industry experience in Biochemistry, Analytical Chemistry, or related discipline.
• Experience with running HPLC and gel-based analytical methods and instrumentation for characterization of proteins/biopharmaceuticals is essential.
• In-depth knowledge of analytical instrumentation, especially Agilent/Thermo HPLCs and Beckman/SCIEX CE, as well as maintaining and troubleshooting analytical equipment are required.
• Ability to independently perform experiments and multi-task with minimal supervision.
• Good verbal and written communication skills are essential.
• Must be able to work collaboratively and efficiently in a team environment.

Preferred Qualifications:

Prior experience in developing and qualifying analytical methods for biopharmaceuticals is highly desirable.

Prior experience in mass spectrometry-based assays for characterization of proteins/ biopharmaceuticals is highly desirable.

Prior experience supporting process and/or Formulation Development is a plus.

How You Will Work:

• Demonstrates collaboration and teamwork. Works well with others and understands that collaboration leads to better results.
• Possesses strong communication skills. Communicates clearly, concisely, and professionally. Listens actively to build understanding.
• Exhibits strong interpersonalskills and self-awareness. Builds and cultivates strong and enduring relationships with others. Acts with humility and understands own strengths and weaknesses.
• Shows continuous improvement and a commitment to self-management and development. Operates with a continuous improvement mindset and continuously seeks to expand own knowledge and capabilities.
• Demonstrates a patient focus. Puts the patient first in actions and decisions taken.

Compensation, Benefits, and So Much More

The expected salary range for this role based on the primary location for this position in California starts at $56.75 per hour. Offer amounts are determined by factors such as experience, qualifications, geographic location, and other job-related factors permitted by law.

A great environment where we work collaboratively, leverage each other's strengths, and work toward a shared vision with our common goals of doing the best thing for patients.

Conditions of Employment

Background investigations are required for all positions at CytomX, consistent with applicable law.

CytomX's Commitment to Diversity, Equity, Inclusion, and Belonging (DEIB)

CytomX believes that DEIB helps drive our success, and we encourage candidates from all identities, backgrounds, and abilities to apply. We are an equal opportunity employer committed to building an inclusive, innovative work environment with employees who reflect our values and ultimately, serve our patients. Therefore, in all aspects of the employment process, we provide employment opportunities to all qualified applicants without regard to race, color, religion, sex, disability, age, sexual orientation, gender identity or expression, pregnancy, medical condition related to pregnancy, creed, ancestry, national origin, marital status, genetic information, or military status, or any other protected status in accordance with applicable law.

Further, we are committed to the full inclusion of all qualified individuals. As part of this commitment, we (and the agencies we work with) will assist individuals who have a disability with any reasonable accommodation requests related to employment, including completing the application process, interviewing, completing any pre-employment testing, participating in the employee selection process, and/or to perform essential job functions where the requested accommodation does not impose an undue hardship. If you have a disability and require reasonable accommodation, or need other assistance in applying for or interviewing for this position, please direct your inquiries to Human Resources, at hr@cytomx.com

Notice to Recruiters/Staffing Agencies

Recruiters and staffing agencies should not contact CytomX Therapeutics through this page. We require that all Recruitment Vendors (e.g., search firms, recruitment agencies and staffing companies) have a fully executed, formal written agreement on file with CytomX prior to submitting candidates. Any resumes submitted through the website or directly by Recruitment Vendors will be considered unsolicited. Unsolicited vendor submissions do not constitute any actual or implied contract with CytomX, and CytomX will not be responsible for any purported fees. For more information, please contact our HR team at hr@cytomx.com

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