Address
Form of workSenior Scientist - TCR Gene Therapy
Gaithersburg, MD
We are seeking a Senior Scientist who is passionate and highly motivated to eradicate cancer using T-cell receptor (TCR) Gene Therapy approaches. As a Senior Scientist, you will be leading from the bench and a member of the in vivo team focused on delivering in vivo datasets that will have a direct impact on the TCR Gene Therapy pipeline. Key responsibilities of this role include:
Accountabilities:
Use your in vivo experience and technical skills to support our goals by designing in vivo adoptive cell therapy experiments, working hands-on in the lab developing and working with various in vivo adoptive cell therapy models of cancer such as xenograft and PDX models, conducting in vivo pharmacology studies (e.g., T-cell persistence, infiltration) and delivering comprehensive in vivo data packages to support TCR Gene Therapy programs. Demonstrate proficiency and flexibility in working with various programs and databases to capture all study data for broad access by project teams and collaborators. Work collaboratively across disciplines to develop and implement aggressive work plans and timelines. Contribute to study reports and presentations.
Essential Skills/Experience:
Desirable Skills/Experience:
Why AstraZeneca?
As Scientists in Oncology, we push the boundaries of science to change the practice of medicine and transform the lives of patients living with cancer. We are a science-based, leading and decisive Oncology enterprise united in our vision to eliminate cancer as a cause of death. The pioneers, we make bold moves that transform the way cancer is treated and truly improve patient outcomes. With one of the broadest and deepest Oncology pipelines in the industry, there are many opportunities to work with new and novel drugs and help discover what's next.
Take a crucial inter-disciplinary approach to save patients' lives! Work at the forefront by taking an inter-disciplinary approach including novel biomarkers, AI, novel endpoints and cutting-edge trial designs. It's because we are constantly innovating that we are able to develop life-changing medicines, change the way cancer is treated and ultimately improve outcomes for patients everywhere.
About Our Gaithersburg Oncology Hub
Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We are dedicated to creating a culture of inclusion and collaboration.
The Gaithersburg site offers a variety of amenities to help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center, game rooms, community garden and more. This is where you'll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams.
Ready to make a difference? Apply now and join us in our mission to eliminate cancer as a cause of death.
Please contact Bobbi Poole, our Talent Acquisition Partner.
Closing Date: February 2, 2024
Competitive remuneration and benefits apply
We offer a competitive Total Reward program including a market driven base salary, bonus and long term incentive. We have a generous paid time off program and a comprehensive benefits package.
Where can I find out more-
Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/
Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/
Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en
AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We follow all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Date Posted
05-Jan-2024
Closing Date
01-Feb-2024Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.
AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.
Gaithersburg, MD
We are seeking a Senior Scientist who is passionate and highly motivated to eradicate cancer using T-cell receptor (TCR) Gene Therapy approaches. As a Senior Scientist, you will be leading from the bench and a member of the in vivo team focused on delivering in vivo datasets that will have a direct impact on the TCR Gene Therapy pipeline. Key responsibilities of this role include:
Accountabilities:
Use your in vivo experience and technical skills to support our goals by designing in vivo adoptive cell therapy experiments, working hands-on in the lab developing and working with various in vivo adoptive cell therapy models of cancer such as xenograft and PDX models, conducting in vivo pharmacology studies (e.g., T-cell persistence, infiltration) and delivering comprehensive in vivo data packages to support TCR Gene Therapy programs. Demonstrate proficiency and flexibility in working with various programs and databases to capture all study data for broad access by project teams and collaborators. Work collaboratively across disciplines to develop and implement aggressive work plans and timelines. Contribute to study reports and presentations.
Essential Skills/Experience:
- PhD degree in a relevant subject area
- Practical in vivo experience and experimental skills in the use of mouse models
- Expertise in immunology
- Experience in common immunological assays (e.g., multicolor flow cytometry)
- Understanding of statistical methods and quality control of data
- Great attention to detail
- Excellent communication, presentation, and organizational skills
- Effective troubleshooting ability
- Ability to work independently and as part of a team
Desirable Skills/Experience:
- Expertise in human T-cell biology
- Expertise in genetically modifying T cells
Why AstraZeneca?
As Scientists in Oncology, we push the boundaries of science to change the practice of medicine and transform the lives of patients living with cancer. We are a science-based, leading and decisive Oncology enterprise united in our vision to eliminate cancer as a cause of death. The pioneers, we make bold moves that transform the way cancer is treated and truly improve patient outcomes. With one of the broadest and deepest Oncology pipelines in the industry, there are many opportunities to work with new and novel drugs and help discover what's next.
Take a crucial inter-disciplinary approach to save patients' lives! Work at the forefront by taking an inter-disciplinary approach including novel biomarkers, AI, novel endpoints and cutting-edge trial designs. It's because we are constantly innovating that we are able to develop life-changing medicines, change the way cancer is treated and ultimately improve outcomes for patients everywhere.
About Our Gaithersburg Oncology Hub
Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We are dedicated to creating a culture of inclusion and collaboration.
The Gaithersburg site offers a variety of amenities to help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center, game rooms, community garden and more. This is where you'll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams.
Ready to make a difference? Apply now and join us in our mission to eliminate cancer as a cause of death.
Please contact Bobbi Poole, our Talent Acquisition Partner.
Closing Date: February 2, 2024
Competitive remuneration and benefits apply
We offer a competitive Total Reward program including a market driven base salary, bonus and long term incentive. We have a generous paid time off program and a comprehensive benefits package.
Where can I find out more-
Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/
Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/
Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en
AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We follow all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Date Posted
05-Jan-2024
Closing Date
01-Feb-2024Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.
AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.
