Senior Analyst, Quality Control

We engineer stem cell transplants that shield healthy cells from targeted therapies
Targeted therapies work by attacking cells that express particular proteins on their surface. Unfortunately, both diseased and healthy cells often express the same proteins, resulting in collateral damage to healthy cells.
At Vor Bio, we engineer hematopoietic stem cells (HSCs) to lack a biologically redundant target protein, then transplant these cells into the patient.
These eHSCs give rise to generations of new healthy blood cells that are effectively shielded from targeted therapies so that only the remaining cancer cells are killed. We are also developing our own CAR-T cell therapy using T cells from the same healthy donor who could potentially provide HSCs for our shielded stem cell transplant and thereby, avoid issues of donor-mismatch. We believe our CAR-T cell therapy may enable more potent and durable responses post-transplant.
Vor Bio is aiming to cure blood cancers through our novel platform combining HSC biology, genome engineering, and targeted therapies to unlock treatment options previously unavailable to patients. Come be a part of a passionate team striving to collaboratively develop a groundbreaking approach to cancer treatment, one of medicine's greatest challenges.
What we value in our fellow Voracians
Passion: Enthusiastically driving our science toward innovative medicines
Fellowship: Fostering genuine bonds of collaboration and mentorship
Humility: Acting selflessly by putting the collective mission first
Who we are looking for:
Vor Bio is seeking an experienced Quality ControlSenior Analyst who will be responsible for executing activities related to establishment / release / testing of raw materials to support GMP manufacturing activities as well as maintaining critical laboratory materials. The individual will also support the stability program for Vor QC by maintaining schedule / pull dates / inventory and reporting. The individual will support environmental monitoring sample collection and testing and be able to assist with EM data review and data trending. This role will report directly to the Associate Director of Quality Control Critical Materials. The position is onsite, based in Cambridge.
Key areas of responsibility:

• Environmental Monitoring sampling, testing, data review and data trending
• Ensuring stability program is current and aligned with industry requirements and internal SOPs.
• Raw Material program support through interface with external partners, and internal cross functional partners
• Work with SMEs to prepare stability reports and laboratory management to schedule internal and external testing as appropriate.
• Continuous improvement of processes that are within area of knowledge / responsibility.
• Work closely with Process team and receiving site QC to make sure that the analytical method transfer timeline align with process transfer timeline.

Qualifications:

• Bachelor's or master's degree in analytical sciences or related fields with minimum 5 years of experience in the development and approval of cell & gene therapy products or biologics or other relevant fields.
• Required experience working in/with clean rooms and proficiency in utilizing aseptic techniques in accordance with industry/compendial standards
• Good communication skills and be able to work cross-functionally with QC, QA, analytical development and CTLs.
• Demonstrated ability to extract scientific details and to multi-task in a high paced environment.
• Experience and knowledge with engineered HSCs and gene editing technologies are preferred.
• Demonstrated collaboration skills working cross functionally, maintain strong stakeholder relationships and influencing scientific rigor.
• Demonstrated ability to draw insights from large data, perform analysis, and present scientific rationale.

By becoming a team member here at Vor, you'll have access to competitive health, dental, and vision coverage, as well as life insurance, and short term and long-term disability insurance. We value work life balance, you'll benefit from discretionary time off, parental leave, and an excellent 401(k) package. We also offer a generous transportation stipend to commute as you wish. We are conveniently located in Cambridge with easy access to public transportation and ample parking.
As an equal opportunity employer, we at Vor Bio know that diversity inspires innovation, inclusiveness, and creativity. We invite you to come as you are. All applicants will be considered for employment agnostic to race, age, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.
Please visit our website at https://www.vorbio.com/ for more information.