Scientist I, Lead Development

The Role: 

The Technology Development group at Life Edit discovers new genome editing systems and establishes new editing capabilities and optimizes them to support efforts developing curative gene editing therapies and gene edited cell therapies. We are looking for an enthusiastic, competent, and self-motivated Scientist with a strong background in mammalian cell culture and genome editing to help expand our technology development platforms and therapeutic capabilities.   

Here’s What You’ll Do: 

• Perform routine cell culture to maintain various cell lines and execute experiments 
• Evaluate Life Edit gene editing systems in mammalian cells to identify optimally engineered systems for further therapeutic discovery and development 
• Lead the formulation of new strategies to improve Life Edit’s genome editors and develop cell-based assays by which to evaluate them
• Analyze experimental data and present scientific results at team research meetings
• Collaborate closely with computational biology, gene editing and preclinical teams
• Maintain meticulous records of experimental methods, tool development and protocols
• Follow current literature in the field of gene therapy and genome editing and attend conferences

Requirements: 

• PhD with 0 - 3 years of applicable experience in Molecular Biology, Cell Biology, or a related field; research experience in genome editing highly preferred
• Experience in culturing, transfecting, and analyzing mammalian cells using cell-based assays (flow cytometry, cell proliferation, and viability assays)—prior experience with primary cell lines is a plus
• Experience with modern molecular biology techniques including DNA/RNA extraction, PCR, qPCR, Flow cytometry and ELISAs
• Prior experience with CRISPR systems and familiarity with NGS techniques is advantageous
• Demonstrated ability to work independently as well as collaboratively in a team-oriented environment
• Exceptional oral and written communication skills

We’re committed to finding the best ways to support our teams so they can do their best work. We take care of our employees, right from the start. 

Health & Wellness 

• Medical, vision, and dental insurance covered at 90%
• Low deductible, no co-insurance and no copays for mental health visits (for in-network care)
• Annual fitness reimbursement

• Employer paid for access to wellness apps and programs like Task Human

Financial 

• Competitive compensation
• 401(k) retirement plans with a 4% employer match and no vesting period
• Employer-paid life insurance and short- and long-term disability insurance
  • Employer-sponsored flexible spending accounts (FSA) and dependent care account (DCA) 
• Access to a 1-on-1 financial advisor
• Commuter reimbursement benefit
• Monthly cell phone stipend

Time Off & Flexibility 

• Unlimited paid time off, including vacation, sick leave, family leave, personal days, and bereavement
• 18 paid company holidays, plus an end-of-year holiday shut down
• 12 weeks of parental leave
• Federal Family and Medical Leave Act (FMLA) and Massachusetts Paid Family and Medical Leave (PFML), administered by Unum

Development Journey 

• Insights Discovery training for every employee to make the most of workplace relationships
• Ongoing professional development, including manager training
• Access to LinkedIn Learning, a self-guided online education platform

Why join Life Edit and the ElevateBio ecosystem?

Life Edit Therapeutics is an integrated subsidiary of ElevateBio, a technology-driven cell and gene therapy company that is accelerating access to the cutting-edge technologies and expertise that can change the future of medicine. Our integrated model combines multiple R&D technology platforms – including Life Edit gene editing – and cGMP manufacturing to power the discovery and development of advanced therapeutics. Our ecosystem is designed to enhance speed, delivery, and probability of success to change patient lives.

Life Edit is an integral part of ElevateBio’s ecosystem of platform technologies and is pioneering focused next-generation gene editing technologies and therapeutics. Located in Durham, NC, members of Life Edit work closely with the ElevateBio Research and Development and BaseCamp manufacturing teams in Waltham, MA. Life Edit is advancing therapeutic programs in collaboration with industry partners while building its own internal pipeline of gene editing therapies. We are looking for a unique individual who can continue to lead the cultural development of Life Edit and build on its momentum as an integral part of the ElevateBio ecosystem.

Our Mission:
To power the creation of life-transforming cell and gene therapies, at a speed the world deserves.

Our Vision:
We seek to be the world’s most indispensable cell and gene therapy technology company, redefining how companies operate, how products are created and how disease is treated.

ElevateBio is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. ElevateBio will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.