Principal Scientist Sample Management

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
About Loxo Oncology at Lilly:
Loxo@Lilly conducts discovery research, clinical development, and regulatory affairs for oncology, with the goal of creating a pipeline of therapies that have the potential to make a meaningful difference for patients. Loxo Oncology at Lilly was created in December 2019, combining the Lilly Research Laboratories oncology organization and Loxo Oncology, which was acquired by Lilly in early 2019. The unit has team members in Boulder, CO, Indianapolis, IN, New York City, NY, South San Francisco, CA, San Diego, CA, Stamford, CT, and Madrid, Spain.
Position Summary:
The Principal Scientist Sample Management will work closely with leadership and team members to help operationalize and maintain a compound management operation. This team will be accountable for establishing and executing SOPs and processes related to storage of inventory, preparation of samples for testing, and shipping/receipt of supplies/samples/compounds for internal/external assays. This role will support compound management activities across multiple geographies, multiple departments and external CROs.
Roles and Responsibilities:

• Assist in implementation of recently purchased capital equipment for expansion of the compound management operation and implement plans for long term, sustainable instrument maintenance.
• Maintain and improve sample workflows associated with storage, manual neat/weigh operations, liquid handling, and delivery of samples to internal and external teams.
• Provide compound registration support.
• Develop tools to simplify internal processes and improve user experience.
• Manage processes associated with international and domestic shipments between collaborators and research sites, ensuring proper documentation is maintained.
• Establish/Maintain a generative safety culture and ensure adherence to safety policies.
• Serve as a steward for the physical compound inventory as well as the associated inventory/output data.
• Test/Validate changes to software, hardware, and procedures. Proactively seek improvements to usability of these systems and production timelines.
• Create and maintain SOPs and job aids for critical processes.
• Troubleshoot software and hardware issues and resolve sample dispensing issues raised by customers.
• Assist laboratory technicians with day-to-day responsibilities, ensuring projects are supported in a timely, consistent manner.
• Establish processes for replenishment of consumables.
• Track production metrics to quantify required changes and subtle operational issues.
• Assist in development, deployment, and change management of enterprise level Sample Management software
• Continue customization of sample software, and work closely with vendors to solve problems
• Maintain effective oral and written communication to Discovery team members (and beyond) and provide support to ensure timelines are met.
• Maintain customer-focused attitude and operation.
• Provide additional support to the Discovery Team (and beyond) as needed.

Required Qualifications:

• A BS/MS or equivalent degree in chemical, biological, engineering sciences or related field with 5+ years working full time in a laboratory setting either in academia or industry.
• Experience programming and maintaining laboratory instruments/automation related to compound management (e.g., storage systems, balances, traditional and acoustic liquid handlers)
• Experience maintaining an inventory of neat and solubilized samples.
• Experience with inventory/request database systems for compound and/or biological Sample Management (LIMS).
• Strong organizational skills and attention to detail.
• Ability to work both independently and within a multidisciplinary team.
• Excellent written, verbal, and interpersonal communication skills are required, with ability to work with/across a range of disciplines including biology, medicinal chemistry and bioassay.

Additional Skills:

• Experience with software and hardware components of relevant automation platforms such as Beckman Echo, Tecan, High Res Biosystems, and automated storage (Hamilton and/or Azenta)
• Experience with automation controlling software such as Cellario, Green Button Go or similar.
• Experience scripting in any relevant languages
• Experience shipping/receiving both domestically and internationally.

Loxo@Lilly (Eli Lilly and Company) currently anticipates that the base salary for this position could range from between $69,000-195,800 and will depend, in part, on the successful candidate's qualifications for the role, including education and experience. Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Loxo@Lilly (Eli Lilly and Company) offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Of course, the compensation described above is subject to change and could be higher or lower than the range described above. Further, Loxo@Lilly (Eli Lilly and Company) reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Loxo@Lilly (Eli Lilly and Company) compensation practices and guidelines will apply regarding the details of any promotion or transfer of Loxo@Lilly (Eli Lilly and Company) employees.
Physical Demands/Travel:
The physical demands of this job are consistent with working in a lab. This job requires the ability to lift up to 25 lbs.
This job will require 10-15% travel time.
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
Work Environment:
This position's work environment is in a lab.
The work environment characteristics describ ed here are representative of those an employee encounters while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform the role and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
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