Predoc Research Associate I

Overview:

A laboratory in the Human Biology Division at Fred Hutchinson Cancer Center is seeking a Predoc Research Associate to work with an interactive collaborative team of scientists investigating the mechanisms of HIV-1 latency and HIV replication using CRISPR screens and validation in T cell and primary cell models.The applicant should be well organized, pay close attention to detail, be reliable and motivated to participate in multiple levels of lab activity.

The Emerman lab has developed a novel screening technology called HIV-CRISPR technology to comprehensively discover the pathways of HIV latency maintenance and HIV replication.This Predoc Research Associate I position will further explore hits from existing and new screens further explore the roles of host proteins in HIV biology in T cells.

Responsibilities:

Essential Functions and Responsibilities

Predoc Research Ascociate will perform standard routine and investigative laboratory work in support of scientific research specific to HIV replication and HIV latency using results from recent CRISPR screens as well as new screens.

Major Duties

• Preform experiments at the bench level to support investigative work, potentially including, but not limited to molecular biology, viral infections and assays, DNA sequencing, PCR amplification, RT-PCR amplification, TC culture, BLS2/3 work, including making virus stocks and performing viral infection.
• CRISPR/Cas9 screening and editing, and analysis of results.
• Experiments with primary T cells.
• Recover, compile and verify accuracy of research data.
• Operate analytical instruments.
• Perform and modify documented protocols and assays.
• Maintain laboratory records and compile data on experiments and assays.
• Interpret and report on experimental results.
• Present data at local and national meetings.
• Prepare manuscripts describing the data and their meaning to the field.

Qualifications:

• Current candidate for doctoral degree in a PhD program in biology or a related field
• Recent graduate work in related field required
• Experience with molecular biology and biochemical method as well as HIV biology.
• A strong interest in research in the area of HIV biology and HIV latency, infectious diseases and global health.
• Evidence of productivity appropriate to a Predoc Res Assc I as measured by publications and presentations, abstracts and posters at conferences.
• Well-organized with strong attention to detail.
• Ability to work independently and perform experiments without day-to-day supervision will be required after training.
• Ability to work as part of a team and to participate in multiple projects in collaboration with different lab members and collaborations with outside labs.

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