Postdoctoral Fellow Molecular Pharmacology Of Feeding Behavior

HOW MIGHT YOU DEFY IMAGINATION?

Youve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared missionto serve patientsdrives all that we do. It is key to our becoming one of the worlds leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.

What you will do

Lets do this. Lets change the world. A postdoctoral position is available to investigate the signaling mechanisms governing Feeding Behavior and energy metabolism at our global headquarters and research site in Thousand Oaks, California. This unique opportunity entails co-mentorship by Dr. Junichiro Sonoda, Ph.D. (Primary PI: Scientific Associate Director, Cardiometabolic Disorders) and Dr. Ki Jeong Lee, Ph.D. (Co-PI: Scientific Associate Director, Discovery Biology). In this vital role, you will be a part of the broader R&D Postdoc Program that focuses on training the next generation of industry scientists. An overwhelming majority of our postdocs go on to advance their careers in industry at leading pharma and biotech companies, including many at Amgen.

You will primarily be investigating a novel GPCR-based signaling mechanism that regulates Feeding Behavior and energy metabolism. The strategic approach involves a combination of multi-omics, proximity labeling, affinity purification, and complementary in vitro and in vivo mechanistic methodologies. Conditional in vivo gene knockout and AAV-mediated gene transduction approaches will also be employed. This comprehensive strategy aims to elucidate the detailed mechanisms of intracellular signal integration through the GPCR in the central nervous system, unveiling novel regulators and mechanisms that control body weight gain.

We are looking for a highly talented, self-motivated individual passionate about science and making groundbreaking discoveries. This role offers a dynamic platform for an ambitious individual to make meaningful advancements in the understanding of Feeding control mechanisms, leveraging Amgen's state-of-the-art technologies within a supportive and stimulating environment that fosters professional growth. The position is for 3 years, with the option to extend for an additional year.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a scientist with these qualifications.

• PhD at the time of appointment

• PhD in the field of biochemistry, signal transduction, molecular biology, cell biology, neurobiology, or a related field

• Demonstrated track record of independent critical thinking and scientific achievement in research, exemplified by a solid peer-reviewed publication record in impactful journals

• Preferred technical expertise in one or more of the following areas: GPCR signal transduction, proximity labeling, affinity purification, in vivo viral transduction, mouse models of metabolic disorders, CRISPR, and multi-omics research

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for our teammates professional and personal growth and well-being.

Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

• Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.

• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

• Award-winning time-off plans and bi-annual company-wide shutdowns

• Flexible work models, including remote work arrangements, where possible

Salary: $82,000 annual base pay

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.