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Salary
Strength Through Diversity
Ground breaking science. Advancing medicine. Healing made personal.
Roles & Responsibilities:
Requirements:
The Center for Disease Neurogenomics (CDN) Panos Roussos at Icahn School of Medicine at Mount Sinai is seeking a highly motivated individual for a Bioinformatician III in Medical Informatics. The post will suit an ambitious and talented individual who is interested in applying his/her/their skills at the interface of human disease and genetics.
The appointed researcher will be embedded in an interdisciplinary team of clinicians, wet lab scientists, bioinformaticians, statistical geneticists and computational biologists. The center studies the genetic mechanisms through which risk genetic variants increase vulnerability for neuropsychiatric traits, including schizophrenia, bipolar disorder, Alzheimer’s disease and eating disorders. Towards advancing genetically based approaches for novel therapeutics discovery and drug repositioning, the center is leading large-scale efforts for generation of large-scale omics data in human brain tissue, including epigenomics and transcriptomics and the use of genome sequencing for big data integration. Distinguishing features of our translational arm of our center is the development of machine learning approaches for phenotyping, genome/transcriptome/epigenome-wide association analysis and the modeling of treatment response. Our population genetics efforts span several biobanks: MVP, BioMe, UKBB, All of Us, as well as smaller cohorts with deep phenotyping. As part of large consortia such as PGC and PsycheMERGE we are participating in global efforts to elucidate the genetic architecture of neuropsychiatric disorders.
Responsibilities
- Develop and implement algorithms, statistical methods and software to analyze large-scale medical informatics data and perform integrative functional analysis.
- Develop and maintain disease databases to annotate and interpret medical record data.
- Implement and maintain phenotyping pipelines leveraging coded and unstructured data (with NLP and/or LLMs).
- Perform rigorous and reproducible data analyses (including longitudinal approaches).
- Develop projects and work independently on a variety of data analysis projects.
- Learn and use bioinformatics tools for processing and analysis of large datasets.
- Identify and resolve technical issues and propose upgrades to current software.
- Publish and present novel research findings in academic journals and conferences.
Qualifications
- M.S. in Biological Sciences, Bioinformatics, Computer Sciences, Statistics or related discipline, PhD preferred.
- Six years minimum experience required with 4+ years of experience in medical informatics (can overlap with e.g. PhD). Experience with data science pipelines, clinical data, and health information technology preferred.
- Firm grounding in statistical methods for medical record data analysis. An outstanding candidate will have experience in developing methods to track and model trajectories in datasets even when information is sparse (e.g. longitudinal treatment and outcome analyses)
- Experience with biological datasets and genetic data is preferred.
- Advanced knowledge of relational and other databases (Oracle, SQL, PL/SQ), statistical software and programming languages, such as R, SAS, SPSS, Matlab, Python and big data management processes.
- Track record of delivering complex scientific projects through high impact factor publications.
- Excellent communication and organizational skills with ability to work to defined timelines, both independently and as part of a multi-disciplinary team.
- An analytical mindset with problem-solving skills.
Employer Description
Strength Through Diversity
The Mount Sinai Health System believes that diversity, equity, and inclusion are key drivers for excellence. We share a common devotion to delivering exceptional patient care. When you join us, you become a part of Mount Sinai’s unrivaled record of achievement, education, and advancement as we revolutionize medicine together. We invite you to participate actively as a part of the Mount Sinai Health System team by:
- Using a lens of equity in all aspects of patient care delivery, education, and research to promote policies and practices to allow opportunities for all to thrive and reach their potential.
- Serving as a role model confronting racist, sexist, or other inappropriate actions by speaking up, challenging exclusionary organizational practices, and standing side-by-side in support of colleagues who experience discrimination.
- Inspiring and fostering an environment of anti-racist behaviors among and between departments and co-workers.
We work hard to acquire and retain the best people and to create an inclusive, welcoming and nurturing work environment where all feel they are valued, belong and are able to professional advance. We share the belief that all employees, regardless of job title or expertise contribute to the patient experience and quality of patient care.
Explore more about this opportunity and how you can help us write a new chapter in our history!
“About the Mount Sinai Health System:
Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 43,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time — discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients’ medical and emotional needs at the center of all treatment. The Health System includes approximately 7,400 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics and top 20 in Cardiology/Heart Surgery, Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report’s “Best Children’s Hospitals” ranks Mount Sinai Kravis Children's Hospital among the country’s best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 14 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek’s “The World’s Best Smart Hospitals” ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally.
The Mount Sinai Health System is an equal opportunity employer. We comply with applicable Federal civil rights laws and does not discriminate, exclude, or treat people differently on the basis of race, color, national origin, age, religion, disability, sex, sexual orientation, gender identity, or gender expression. We are passionately committed to addressing racism and its effects on our faculty, staff, students, trainees, patients, visitors, and the communities we serve. Our goal is for Mount Sinai to become an anti-racist health care and learning institution that intentionally addresses structural racism.”
EOE Minorities/Women/Disabled/Veterans
Compensation
The Mount Sinai Health System (MSHS) provides a salary range to comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $96461 - $144692 Annually. Actual salaries depend on a variety of factors, including experience, education, and hospital need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.
