The Bioinformatician II develops and implements novel approaches in translational medicine or applies analytic and interpretive methods to integrate a wide variety of observational health and genomic data and leverage it towards improving treatment and prevention. Our goal is to use these data to improve diagnostics, identify novel treatments, and offer clinical insights into rare genetic disorders. We aim to deliver clinical applications into practice that will help shorten the diagnosis odyssey and target treatment and care to individuals’ health profiles rather than relying on a one-size-fits-all model, in order to improve patient outcomes. We are developing innovative new tools that address a range of needs using a vast repository of health and genomic data.
This position is temporary, and while there is no set end date, it is intended to fulfill short-term staffing needs within our department.
Responsibilities
- Develop and apply novel computational methods for disease subtype stratification and digital phenotyping algorithm. Collaborate with team members and other scientists in multidisciplinary manner.
- Build machine learning or deep learning pipelines to assess risk for a number of diseases using integrated big data from various data sources, including genetics, genomics and electronic medical records data.
- Identify novel indications or adverse events for medications prescribed to patients in certain settings, in order to recommend strategies to improve standard of care.
- Work with a cross-functional team setting to use aggregated patient data to assess a variety of clinical questions.
- Other related duties as assigned.
Qualifications
- M.S. in Bioinformatics, Biomedical Informatics, Computational Biology, or Genomics. Alternately, M.S. in a discipline requiring strong computational and analytical skills supplemented with some biology exposure. Ph.D in a related field preferred. Those with a Bachelors degree and additional post-graduate experience are considered.
- 2+ years post-graduate experience in a research environment, including the manipulation of large biological datasets.
- Extensive experience in machine learning with a proven track record of developing and applying advanced computational techniques to solve complex disease problems
- Proven experience in developing AI models for real-world environments and integrating ML into large-scale production applications.
- Knowledge of advanced machine learning methodologies such as deep learning, architectures and familiarity with at least one DL library (e.g., Tensorflow, Theano, PyTorch, Caffe)
- Experience with NLP and text mining is a plus.
- Highly proficient in programming and scripting in at least one language (R, Python, etc.)
- Experience with SQL databases
- Experience working with high-performance computing clusters, especially ones designed for AI/machine learning applications, such as AWS
- Familiarity with Common Data Models, such as OMOP CDM from OHDSI, is an advantage
Employer Description
Strength Through Diversity
The Mount Sinai Health System believes that diversity, equity, and inclusion are key drivers for excellence. We share a common devotion to delivering exceptional patient care. When you join us, you become a part of Mount Sinai’s unrivaled record of achievement, education, and advancement as we revolutionize medicine together. We invite you to participate actively as a part of the Mount Sinai Health System team by:
- Using a lens of equity in all aspects of patient care delivery, education, and research to promote policies and practices to allow opportunities for all to thrive and reach their potential.
- Serving as a role model confronting racist, sexist, or other inappropriate actions by speaking up, challenging exclusionary organizational practices, and standing side-by-side in support of colleagues who experience discrimination.
- Inspiring and fostering an environment of anti-racist behaviors among and between departments and co-workers.
We work hard to acquire and retain the best people and to create an inclusive, welcoming and nurturing work environment where all feel they are valued, belong and are able to professional advance. We share the belief that all employees, regardless of job title or expertise contribute to the patient experience and quality of patient care.
Explore more about this opportunity and how you can help us write a new chapter in our history!
“About the Mount Sinai Health System:
Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 43,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time — discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients’ medical and emotional needs at the center of all treatment. The Health System includes approximately 7,400 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics and top 20 in Cardiology/Heart Surgery, Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report’s “Best Children’s Hospitals” ranks Mount Sinai Kravis Children's Hospital among the country’s best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 14 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek’s “The World’s Best Smart Hospitals” ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally.
The Mount Sinai Health System is an equal opportunity employer. We comply with applicable Federal civil rights laws and does not discriminate, exclude, or treat people differently on the basis of race, color, national origin, age, religion, disability, sex, sexual orientation, gender identity, or gender expression. We are passionately committed to addressing racism and its effects on our faculty, staff, students, trainees, patients, visitors, and the communities we serve. Our goal is for Mount Sinai to become an anti-racist health care and learning institution that intentionally addresses structural racism.”
EOE Minorities/Women/Disabled/Veterans
Compensation
The Mount Sinai Health System (MSHS) provides a salary range to comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $16 - $50 Hourly. Actual salaries depend on a variety of factors, including experience, education, and hospital need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.