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Johnson & Johnson is currently seeking an Associate Scientist to join our Translational Sciences (TS), Immunology Translational Sciences and Medicine (TSM) team located in San Diego, CA.
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/.Janssen Immunology has a history of bringing life-changing therapies to patients with immune-mediated diseases.
Translational Sciences and Medicine (TSM) is an integrated group of scientists composed of a clinical Translational Medicine (TM) team which conducts early clinical development and experimental medicine studies, and a Translational Sciences (TS) team which uses human based data and tissues to support the end-to-end portfolio. Together, the TSM group will provide the key learnings/insights on the next wave of novel therapies for these patients. Organizationally, TSM serves as a pivotal bridge between Discovery Research and the later phase Clinical Development group. TSM provides the necessary scientific and clinical expertise to advance an industry-leading pipeline of novel mechanism small molecules and biologic agents to address unmet need in immune-mediated diseases.
TS has a broad remit stretching from support of discovery with human data to support target selection, through development of novel decision- making biomarkers for early phase clinical trials, target-centric indication sequencing and prioritization, and biomarker support of regulatory filings. It has expertise in biomarker development, disease biology research and in the application of immunology and data science technologies to support drug discovery and development.
This position will reside within the GI group in Immunology Translational Sciences department and requires a highly motivated and detail-orientated candidate to for the clinical progression of innovative therapies across immunologic diseases. The successful candidate will be expected to contribute to the execution of biomarker plans and bring an enthusiastic mindset to the team.
The successful candidate will be effective in the execution and troubleshooting of lab experiments for human-based in vitro/ex vivo stimulation models and perform ELISA-based assays and proteomics/transcriptomics experiments, including Olink and RNAseq. Further, the candidate will operate in a highly collaborative environment with members of TS and the Discovery organization and will follow best practices for Data Integrity complying with organization and company standard operating procedures in a timely fashion, such as training and project time accounting.
Responsibilities are as follows:
- Support implantation of Olink platform (target and explore) at La Jolla for serum proteomics analysis and internalizing ELISA-based clinical assays at La Jolla site
- Perform experiments to support biomarker programs across various stages of clinical trials and provide biomarker data packages in timely manner with high quality
- Execute, and troubleshoot molecular and/or cellular assays for patient stratification in clinical trials for the Immunology Therapeutic Area
- Work closely with other lab-based personnel within Biomarkers to ensure optimal laboratory environment (collaboration, culture, safety, etc.)
Qualifications
- B.S. in biology or related area with at least 1 years of relevant experience is required, preferably in pharmaceutical.
- Experience with the following molecular biology techniques/platforms is required: hands-on experiences of Olink HT Proteomics analysis, RNA/protein extraction, Flow cytometry, ELISA/MSD/Luminex/Singulex
- Human-based tissue explant experience is highly preferred.
- Experience with flow cytometric assays (examples include Symphony, CyTOF).
- Excellent communication skills
The anticipated base pay range for this position is $88,000 to $129,605.
Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.
Employees may be eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)).
This position is eligible to participate in the Company’s long-term incentive program.
Employees are eligible for the following time off benefits:
· Vacation – up to 120 hours per calendar year
· Sick time - up to 40 hours per calendar year
· Holiday pay, including Floating Holidays – up to 13 days per calendar year
· Work, Personal and Family Time - up to 40 hours per calendar year
Additional information can be found through the link below. For additional general information on Company benefits, please go to: https://www.careers.jnj.com/employee-benefits
Johnson & Johnson Family of Companies are equal opportunity employers, and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, genetic information, national origin, protected veteran status, disability status, or any other characteristic protected by law.
