Address
Form of workAssociate Scientist - Early Oncology, Tumor Targeted Delivery
Gaithersburg, MD
Are you a highly motivated and independent Associate Scientist with a passion for cancer biology? Do you have a track record of scientific excellence within in vitro cancer modelling? If so, we have an exciting opportunity for you to join our antibody-drug conjugate (ADCs) Platform team in Gaithersburg, MD USA. As a key member of our team, you will be instrumental in delivering all aspects of pharmacology support, establishing assay systems and delivering datasets that will directly impact the drug discovery process and pipeline. Join us and learn from our diverse team of the brightest minds as we seamlessly and inclusively work together. It's where the best of both academia and industry come together to share knowledge, grow together and build meaningful careers.
Accountabilities
In this fully laboratory-based position within the Early Oncology ADC Platform Development Team, you will develop, design, conduct and analyze in vitro experiments to assist in the development of our next generation ADC therapeutics. You will help evaluate how changes to our antibodies, linkers and payloads can optimize the therapeutic index of our ADCs. You will be expected to support cross-functional teams and work collaboratively with project managers to ensure the timely generation and dissemination of critical program data. As a highly organized, self-motivated individual with a strong background in laboratory science, you will stay up to date with relevant technical and intellectual scientific expertise in the ADC field, tumor biology and cancer modelling. You may also conduct ex vivo analyses of our ADCs based on interest and experience.
Essential Skills/Experience:
Desirable Skills/Experience:
At AstraZeneca's Oncology R&D department, we push the boundaries of science to change the practice of medicine and transform the lives of patients living with cancer. We are a science-based, leading and decisive Oncology enterprise united in our vision to eliminate cancer as a cause of death. With one of the broadest and deepest Oncology pipelines in the industry, there are many opportunities to work with new and novel drugs and help discover what's next. We foster a mindset of courage, where everyone is empowered to step up, innovate and work at pace. Our commitment to patients and pioneering spirit are truly embedded and it's what makes our pipeline unique.
About Our Gaithersburg Oncology Hub
Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We are dedicated to creating a culture of inclusion and collaboration.
The Gaithersburg site offers a variety of amenities to help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center, game rooms, community garden and more. This is where you'll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams.
Are you ready to make a meaningful difference in the world of Oncology? Apply today and join us in our mission to eliminate cancer as a cause of death!
Closing Date: February 7, 2024
Competitive remuneration and benefits apply
We offer a competitive Total Reward program including a market driven base salary, bonus and long term incentive. We have a generous paid time off program and a comprehensive benefits package.
Where can I find out more?
Our Social Media, Follow AstraZeneca on LinkedIn
https://www.linkedin.com/company/1603/
Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/
Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en
AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We follow all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Date Posted
11-Jan-2024
Closing Date
06-Feb-2024Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.
AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.
Gaithersburg, MD
Are you a highly motivated and independent Associate Scientist with a passion for cancer biology? Do you have a track record of scientific excellence within in vitro cancer modelling? If so, we have an exciting opportunity for you to join our antibody-drug conjugate (ADCs) Platform team in Gaithersburg, MD USA. As a key member of our team, you will be instrumental in delivering all aspects of pharmacology support, establishing assay systems and delivering datasets that will directly impact the drug discovery process and pipeline. Join us and learn from our diverse team of the brightest minds as we seamlessly and inclusively work together. It's where the best of both academia and industry come together to share knowledge, grow together and build meaningful careers.
Accountabilities
In this fully laboratory-based position within the Early Oncology ADC Platform Development Team, you will develop, design, conduct and analyze in vitro experiments to assist in the development of our next generation ADC therapeutics. You will help evaluate how changes to our antibodies, linkers and payloads can optimize the therapeutic index of our ADCs. You will be expected to support cross-functional teams and work collaboratively with project managers to ensure the timely generation and dissemination of critical program data. As a highly organized, self-motivated individual with a strong background in laboratory science, you will stay up to date with relevant technical and intellectual scientific expertise in the ADC field, tumor biology and cancer modelling. You may also conduct ex vivo analyses of our ADCs based on interest and experience.
Essential Skills/Experience:
- Bachelor's degree with >2 years of research experience in cancer/cell biology, or Master's degree in cancer/cell biology. Prior experience in the biopharmaceutical industry preferable.
- Experience with routine cell culture, particularly culture of tumor cells
- Experience assessing in vitro activity of therapeutic compounds via assays to determine binding and internalization (e.g. flow cytometry or ligand-binding assays), cytotoxicity (e.g. CellTiterGlo assays), and mechanism of action (e.g. Western Blot analysis)
- Works independently with minimal supervision to conduct experiments
- Excellent communication and presentation skills to report data in a clear and concise manner, with a clear understanding of its implications within the overall context of drug discovery
- Strong interpersonal and collaboration skills together with evidence of delivery in a team-oriented, collaborative environment
- A proven track record of productivity; contributions to scientific publications in peer-reviewed journals preferred
Desirable Skills/Experience:
- Experience in evaluation of ADCs
- Experience running combination screening assays
- Experience with high throughput screening (e.g. use of equipment such as the ECHO acoustic liquid handler)
- Experience with flow cytometry and relevant analysis software (e.g. FlowJo)
- Knowledge of the industrial drug discovery process
At AstraZeneca's Oncology R&D department, we push the boundaries of science to change the practice of medicine and transform the lives of patients living with cancer. We are a science-based, leading and decisive Oncology enterprise united in our vision to eliminate cancer as a cause of death. With one of the broadest and deepest Oncology pipelines in the industry, there are many opportunities to work with new and novel drugs and help discover what's next. We foster a mindset of courage, where everyone is empowered to step up, innovate and work at pace. Our commitment to patients and pioneering spirit are truly embedded and it's what makes our pipeline unique.
About Our Gaithersburg Oncology Hub
Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We are dedicated to creating a culture of inclusion and collaboration.
The Gaithersburg site offers a variety of amenities to help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center, game rooms, community garden and more. This is where you'll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams.
Are you ready to make a meaningful difference in the world of Oncology? Apply today and join us in our mission to eliminate cancer as a cause of death!
Closing Date: February 7, 2024
Competitive remuneration and benefits apply
We offer a competitive Total Reward program including a market driven base salary, bonus and long term incentive. We have a generous paid time off program and a comprehensive benefits package.
Where can I find out more?
Our Social Media, Follow AstraZeneca on LinkedIn
https://www.linkedin.com/company/1603/
Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/
Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en
AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We follow all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Date Posted
11-Jan-2024
Closing Date
06-Feb-2024Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.
AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.
