Senior Research Scientist; Dmpk

SENIOR RESEARCH SCIENTIST, DMPK in Buffalo, NY

Curia provides global contract research and manufacturing services to the pharmaceutical and biotechnology industries.

The Senior Research Scientist, DMPK is an expert in the areas of DMPK and drug bioanalysis and metabolism. The principal responsibilities of the Senior Research Scientist are to execute research projects in these areas, as well as provide technical expertise to prepare cost estimates for non-standard business proposals and to expand capabilities and improve efficiencies for DMPK studies.  The Senior Research Scientist is expected to demonstrate expertise in both the theoretical and practical aspects of mass spectrometry, to apply this expertise to the tasks assigned, and to develop novel assays and services as needed. Effective communication and multitasking skills, and the ability to deliver independent results within a team environment are all integral to this position. The Senior Research Scientist is encouraged to display a degree of professionalism reflected in part by increasing the scientist's knowledge of theory and practice through reading scientific journals and texts. Over time the Senior Research Scientist is expected to demonstrate an aptitude for the mentorship and development of less experienced DMPK scientists. 
 

Join our talented workforce, where a commitment to excellence and a customer focused attitude is everything. We pursue excellence because our work has the power to improve patients' lives with the pharmaceuticals we develop and manufacture.

We proudly offer

• Generous benefit options (eligible first day of employment) 
• Paid training, vacation and holidays (vacation accrual begins on first day of employment)
• Career advancement opportunities 
• Education reimbursement
• 401k program
• Pension (for union employees)
• Learning platform

And more! 

Essential Duties and Responsibilities

• Provide specific technical expertise to execute research projects in the areas of DMPK, bioanalysis and/or metabolite synthesis
• Particular focus on bench execution of DMPK assays with ability to cross train (and provide cross training) on additional assays as needed
• Design and conduct in vitro experiments in liver microsomes or hepatocytes to generate compound metabolites, characterize metabolic pathways, evaluate metabolism kinetics, determine bioactivation mechanisms, etc.
• Use sound judgment and previously acquired knowledge and experience to develop new procedures. These procedures may go beyond the normal routine and involve literature searching as well as contact with suppliers and customers, etc.
• Advise and/or train other DMPK scientists for the efficient conduct of ADME assays and appropriate evaluation of assay performance and results
• Supervision, development and performance monitoring of direct reports and others, as may be assigned by the Head of the DMPK team
   

Education and/or Experience

• Ph.D. in Biochemistry, Biology, Pharmaceutical Science, Analytical Science, Chemistry or related field with  a preference for 1-3 years of relevant industry research experience
  OR
• Master's degree with at least 8 years of experience in a DMPK laboratory
• Comprehensive understanding and experience in mass spectrometry, bioanalytical methods development (and validation), in vitro ADME and PK/PD techniques
   

Knowledge, Skills and Abilities

• Candidate should have fundamental understanding of various DMPK areas such as physicochemical properties, PK, drug metabolizing enzyme and transporter kinetics, and mechanisms of bioactivation
• Hands-on experience and strong trouble shooting skills for LC-MS/MS bioanalysis
• Ability to write routine reports and correspondence
   

Salary: $80,500/yr.

Education, experience, location and tenure may be considered along with internal equity when job offers are extended.

All interested applicants must apply online. Please be aware of scammers. Curia will only send offer letters and requests for sensitive personal information from a curiaglobal.com email address. Curia is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. Curia is an E-Verify employer.

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