Scientist / Manager

The Position
Roche Diagnostics acquired Stratos Genomics (SBX Nanopore Sequencing) in 2020 for its novel Sequencing by eXpansion (SBX™) technology. SBX™ uses unique applications from chemistry, biochemistry, electrochemistry, and protein engineering to sequence DNA by nanopore in rapid time with high accuracy and at a low cost. The successful candidate will join the SBX Detection Sequencing department to further develop our sequencing technology through research and development efforts while guiding a team of direct reports.
The Sequencing team is devoted to developing our high throughput, low-cost DNA sequencing approach into an industry disrupting product that will facilitate the care that patients need. We are looking for a motivated scientist with management background to grow and lead a team of researchers striving towards elevating performance of our complex sequencing system. This position will require taking a whole system approach that addresses the interconnected dynamics of nanopore structure, Xpandomer design, sequencing conditions, fluidics, redox reactions, and surface chemistries. Please include a cover letter outlining why you want to work with us, your specific interest in our technology, and how you would contribute to our success.
Responsibilities:

• After mastering execution of our current work processes and established SOPs, continue to advance research and development efforts on our multifaceted nanopore-based sequencing platform.
• Use technical and theoretical understanding to propose detailed plans for executing high quality and complex laboratory experiments while keeping processes well organized and documented.
• Communicate actively, effectively, and promptly with supervisor on project status, significant findings, data analysis summaries, critical problem areas, and pathways forward.
• Manage, mentor, and train direct reports to comply with expectations while fostering an environment that develops new and existing skills to support departmental goals.
• Support management decisions and goals in a positive, professional manner. Embrace priorities and responsibilities set forth by management.
• Collaboratively work with manager and colleagues to explore alternative approaches to solve problems and find solutions. Make data-driven recommendations to solve problems with feasible solutions.
• Analyze and interpret experimental data using various data analysis software (e.g., Excel, Python) and/or applying quantitative methods. Summarize experimental results with a keen observational eye to anomalies, deviations, and new paths of inquiry. Prepare pithy data reviews, conclusions, and actionary plans for manager.
• Use technical writing/presentation skills to produce comprehensive & concise reports/documents in a timely manner. When needed, effectively present findings to team members and senior management.
• Maintain databases to track performance, project progress, and experimental findings.
• Require minimal guidance to manage tasks and work time responsibly. Take personal accountability to deliver on assigned tasks promptly. Independently manage own work flow.
• Maintain electronic lab notebook documentation. Ensure that all experimental methods and results are recorded timely, accurately, consistently, and according to established formats.
• Participate in routine lab maintenance, lab safety, ISO, and QSR implementation.
• Maintain performance of and troubleshoot issues encountered while working on various instruments.
• Maintain clean and organized personal and communal lab spaces.
• Perform work according to established internal safety guidelines and procedures, and as specified by appropriate external regulatory agencies (e.g., OSHA). Make recommendations and act as appropriate to keep the lab a safe environment for all team members, including regular housekeeping tasks.
• Adhere to Roche Diagnostics Seattle policies and complete any additional duties as assigned.

Minimum Qualifications:

• Doctorate, Master's or Bachelor's degree in Molecular biology, Protein Engineering, Bioengineering, Biochemistry or related field, or equivalent combination of education and work-experience
• 5 years related research & development experience
• 2 years management experience
• Ability to execute relevant laboratory experimentation with appropriate controls.
• Ability to recognize and resolve problems encountered in experimental procedures.
• Mastery of basic laboratory techniques (e.g., pipetting, sterile technique, solution preparation, etc.).
• Comfortable with standard molecular biology techniques, mutagenesis, protein expression/purification
• Very good organization skills with excellent attention to detail.
• Advanced comfort with Google Docs & Microsoft office suite

Preferred Qualifications:

• Previous experience working with nanopores or sequencing technologies.
• Experience with nanopore or transmembrane protein expression/purification
• Experience with AKTA FPL
• Experience with coding or programming applications (e.g., Python, Matlab, etc.).
• Experience with AKTA Unicorn, Pyml, and Geneious

Relocation benefits are not offered for this role. The expected salary range for this position based on the primary location of Seattle, WA is $116,120 and $145,200 Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed here: Benefits
Who we are
At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.
Roche is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individual's race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.