Scientist I/Ii - R&D

Eitr Biologics, Inc., (Eitr) is a San Diego, CA based biotechnology company focused on the pursuit of novel next generation immunotherapeutics for the treatment of infectious diseases that are a current or emerging threat to public health. Our scientific approach emphasizes the development of technologies that will increase global accessibility to lifesaving immunotherapeutics. Eitr has fostered a robust and highly collaborative worldwide network of academic and government laboratories that share in our scientific goal to address unmet public health needs. Eitr scientists can expect to work in a collaborative atmosphere to advance promising early-stage exploratory technologies to clinical stages of drug development.

Eitr currently has an opening for a Scientist I/II - Research and Development position. The Scientist I/II - R&D will be an integral part of the Research and Development team, whose primary focus is on identifying and characterizing therapeutic candidates.

Responsibilities

• Construct design, molecular cloning, multi-piece DNA assembly, site-directed mutagenesis and preparation of phage libraries
• Design and perform phage display based experiments (e.g., cloning, panning/screening, sequencing, etc.)
• Generate and characterize stable mammalian cell lines
• Characterize antibodies and antibody-based therapeutics (for e.g. affinity, specificity, cross-species binding, epitope determination)
• Records experimental data, writes data summaries in digital lab notebook
• Draft technical reports, as necessary
• Perform protein expression experiments
• Performs experiments including SDS-PAGE, UV/Vis Spectroscopy, ELISA, BLI and Western Blot
• Ensures lab cleanliness and safety by maintaining equipment and technician attire, and keeping all samples properly labeled and stored
• Maintains common lab supply stocks as needed and general lab maintenance
• Performs internet searches to gather relevant information, record and present any relevant findings in a manner pursuant to facility protocol
• Other duties as assigned

Requirements

Basic Qualifications

• Master's Degree. in a biology related discipline with 6+ years of experience in an academic and/or industry setting
• Demonstrated mastery of standard molecular biology techniques (e.g., primer design, DNA/RNA preparations, PCR, cloning)
• Experience with antibody phage display including library construction, panning, screening by ELISA and FACS, and characterization
• Strong desire to formulate and execute experimental designs in an efficient manner.
• Experience with mammalian cell tissue culture and cell development
• Knowledge of protein biochemistry
• Ability to follow written procedures/protocols precisely
• Ability work independently to complete given tasks
• Good communication, interpersonal, and teamwork skills are essential

Preferred Qualifications

• Ph.D. in a biology related discipline with 0-4 years of experience in an academic and/or industry setting
• Experience with electronic or digital lab notebooks and data entry
• Experience with broad set of cell-based assays including reporter assays, FACS competition, ADCC, ADCP, CDC
• Experience with Biolayer Interferometry
• Experience independently designing and troubleshooting experiments
• Experience with infectious disease immunotherapeutics
• Familiar with Cytiva AKTA FPLC systems and Unicorn software
• Experience with antibody formats including ScFv, IgG, VHH, & multi-specifics
• Experience with protein tag-based affinity and FPLC based chromatography, SDS-PAGE, Western Blot, and spectrophotometric analysis

Benefits

• Health Care Plan (Medical, Dental & Vision)
• Retirement Plan (401k)
• Life Insurance
• Paid Time Off (Vacation, Sick & Holidays)
• Family Leave (Maternity, Paternity)
• Training & Development

Compensation

Eitr reasonably expects the annual base compensation for this role to be between $95,000 and $130,000. Specific offer details are determined by carefully considering a variety of factors, including the candidate’s skills, experience, education, market demands, and internal parity.

EEO Employer

Eitr is committed to a policy of Equal Employment Opportunity and will not discriminate against an applicant or employee based on race, color, religion, creed, national origin or ancestry, sex, age, physical or mental disability, veteran or military status, genetic information, sexual orientation, or any other legally recognized protected basis under federal, state, or local law. The information collected by this application is solely to determine suitability for employment, verify identity, and maintain employment statistics on applicants.

Eitr is also committed to providing reasonable accommodations to individuals with disabilities. If you need a reasonable accommodation for any part of the employment process, please let us know the nature of your request and your contact information.

Eitr is not currently hiring foreign national applicants that require or will require sponsorship tied to a specific employer, such as H, L, TN, F, J, E, O.