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SalaryWe are seeking a highly motivated Scientist II to join our Analytical Development team at Ensoma. In this role, you will organize, schedule and deliver data to support internal teams at Ensoma. You will supervise routine sample testing while tracking and trending data, as well as draft reports. You will also support external sample testing, data and documentation review, and contribute to internal and external method qualifications.
You will use your proven track record of timely project completion, executing protocols and presenting results in multiple formats to deliver a high quality of work. As needed, you will also use your expertise to troubleshoot experimental protocols in concert with colleagues across the CMC team. Join us and be part of a company moving novel gene therapies into the clinic, revolutionizing the reach and access of the curative power of genomic medicines for patients with serious diseases.
Responsibilities:
- Lead routine sample analysis, supervising laboratory activity and as needed, perform methods including digital PCR (dPCR), qPCR, cell-based assays, and ELISA-type assays.
- Guide data workflow development and improve existing practices to reduce turnaround time without sacrificing quality.
- Manage sample testing queue.
- Provide expertise and draw from laboratory experience to solve technical problems to meet aggressive timelines.
- Build and apply appropriate statistical models, maintain accurate records, review electronic laboratory notebook entries including reviewing accuracy in data analysis, and generate data-driven reports.
- Contribute to writing and revising SOPs, development reports and/or other documentation as needed.
- Maintain a professional laboratory environment and data delivery schedules.
- Other duties and responsibilities as assigned
Qualifications:
Required:
- A PhD in Analytical Chemistry, Biochemistry, Molecular Biology, or related field with at least two years of relevant post-graduate experience in a CMC setting driving routine assay workflows
- Expertise in molecular analytics, especially qPCR and dPCR
- Experience supporting high throughput testing environments, familiarity with liquid handlers, laboratory automation and data workflow development.
- Experience working with statistical software and lab notebook software (Benchling, JMP, Prism). Capable and comfortable being the administrator for laboratory software packages.
Preferred:
- Professional experience managing and training junior employees.
- Familiarity with building and iteratively improving data generation and review workflows. Database knowledge is a plus.
- Experience working with large datasets, with the ability to review data for accuracy and build and apply statistical models to large datasets
- Track record successfully contributing to cross-functional process improvement teams
About Ensoma:
Ensoma is a place where you can ask the big questions. We look at gene therapy today and ask: What if we could eliminate the patient burden? What if we could treat diseases that affect millions? What if we could treat people anywhere around the world?
Ensoma was founded to answer these questions through our Engenious™ platform that can transform the hematopoietic (blood & immune) system with a single treatment. Our Engenious gene therapy platform is the first to precisely engineer any or all hematopoietic and immune cells with a one-time, off-the-shelf in vivo treatment. Engenious therapies have an unmatched capacity to deliver all modern genetic modification tools and set a new standard for versatile cell programming and control across a range of complex diseases. We believe the future of medicine lies within us – and this bigger, bolder vision for gene therapy needs incredible people to make it a reality.
For our team, realizing this vision is personal. Founded and guided by leaders drawn from the top of the cell and gene therapy field, we feel an urgency and passion for our work driven by its potential global impact.
A meeting at Ensoma is a space where curiosity, trust, authenticity, problem-solving and professional development are celebrated. A career at Ensoma is an opportunity to be part of the team building the future of medicine.
Ensoma is a 5AM Portfolio company supported by top-tier investors, strategic partners, and a passionate team committed to a bold global vision for genomic medicines. Ensoma is headquartered in Boston, Massachusetts and has operations in Copenhagen, Demark. For more information, please visit www.ensoma.com.
