Scientist, Formulation, Maps

We are leading the way in developing a broad portfolio and innovative pipeline of vaccines to make an impact for society. We deliver over two million vaccine doses per day to people living in over 160 countries.

By leveraging a novel and highly efficient vaccine technology - called Multiple Antigen Presenting System (MAPS) - enables the high-affinity binding of protective polysaccharides as well as proteins in a single vaccine, uniquely inducing a broad and protective B-cell and T-cell immune response - we continue to get ahead of disease together.

We have an exciting new opportunity in our Formulation Development team. We are looking for a highly motivated scientist to work with our experience, energetic, and passionate team to develop a novel formulation to support our exciting MAPS technology.

Key responsibilities:

• Contribute to pre-formulation and formulation development for multi-valent vaccines.
• Conduct laboratory-based analytical chemistry, biophysical characterization, and formulation research activities.
• Execute hands-on experiments, collect data, and perform data analysis independently to support both drug substance and drug product formulation screening and development.
• Help design and select stable formulations and implement scalable processes.
• Maintain excellent documentation of all work including electronic lab notebooks, test methods, and protocols.
• Prepare and deliver concise scientific presentations of experimental results and assist in authoring detailed scientific technical reports.
• Work closely and build a strong collaboration with Analytical Development and Process Development teams to execute stability studies on selected formulation candidates.
• Oversee maintenance of key laboratory equipment and perform simple maintenance activities.
• Understand and adhere to corporate standards regarding code of conduct, safety, and GxP compliance.

Why you?

Basic Qualifications:

• Ph.D. in Protein Chemistry (or equivalent, e.g., Bioengineering, Chemical Engineering, Biochemistry, Biophysics, Pharmaceutical Sciences)
• Hands-on experience in protein biochemical and biophysical characterization, developability assessment, and stress stability studies in support of formulation development.
• Detailed knowledge of protein structure, protein stability, biophysical characterization, formulation screening, and development.
• Strong expertise in protein biophysical and biochemical characterization techniques, including size-exclusion chromatography (SEC), cation exchange chromatography (CEX), hydrophobic interaction chromatography (HIC), Heparin affinity HPLC, differential scanning calorimetry (DSC), differential scanning fluorimetry (DSF), dynamic light scattering (DLS), size-exclusion multi-angle light scattering (SEC-MALS), UV-vis and fluorescence spectroscopy, imaged capillary isoelectric focusing (icIEF), capillary electrophoresis sodium dodecyl sulfate (CE-SDS), particle and viscosity measurements. Must be willing and able to learn new technologies as needed.
• Demonstrated track record of independent thinking, creativity, and scientific accomplishment.
• Highly responsible and self-motivated with the ability and desire to work in a fast-paced environment and ensure high quality and timely deliverables.
• Great team player and work ethic with excellent collaboration and communication skills.

Preferred Qualifications:

• 1-3 years of relevant biopharmaceutical industry experience preferred.

Why GSK?

We want GSK to be a workplace where everyone can feel a sense of belonging and thrive. We're committed to being more proactive at all levels so that our workforce reflects the communities we work and hire in, and our GSK leadership reflects our GSK workforce.

We're also working hard to become more inclusive in the way we do business. We're building demographic planning into our clinical trials, so they reflect the real-world population that's affected by the disease we're studying. We're engaging with diverse-owned suppliers that meet our standards and share our values. We're also inspiring the next generation of diverse scientists by investing in STEM education programmes to improve career opportunities for people in under-represented communities.

GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years.

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a workplace where everyone can feel a sense of belonging and thrive as set out in our Equal and Inclusive Treatment of Employees policy. We're committed to being more proactive at all levels so that our workforce reflects the communities we work and hire in, and our GSK leadership reflects our GSK workforce.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).

GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

At GSK, the health and safety of our employees are of paramount importance. As a science-led healthcare company on a mission to get ahead of disease together, we believe that supporting vaccination against COVID-19 is the single best thing we can do in the US to ensure the health and safety of our employees, complementary workers, workplaces, customers, consumers, communities, and the patients we serve.

GSK has made the decision to require all US employees to be fully vaccinated against COVID-19, where allowed by state or local law and where vaccine supply is readily available. The only exceptions to this requirement are employees who are approved for an accommodation for religious, medical or disability-related reasons.

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