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SalaryCompany Overview
Since its inception over a decade ago, CRISPR Therapeutics has transformed from a research-stage company advancing programs in the field of gene editing, to a company with a diverse portfolio of product candidates across a broad range of disease areas including hemoglobinopathies, oncology, regenerative medicine, cardiovascular and rare diseases. The Nobel Prize-winning CRISPR science has revolutionized biomedical research and represents a powerful, clinically validated approach with the potential to create a new class of potentially transformative medicines. To accelerate and expand its efforts, CRISPR Therapeutics has established strategic partnerships with leading companies including Bayer and Vertex Pharmaceuticals. CRISPR Therapeutics AG is headquartered in Zug, Switzerland, with its wholly-owned U.S. subsidiary, CRISPR Therapeutics, Inc., and R&D operations based in Boston, Massachusetts and San Francisco, California, and business offices in London, United Kingdom.
Position Summary
CRISPR Therapeutics is seeking a highly motivated Research Associate to join our In Vivo Technical Operations department in Boston, Massachusetts. The incumbent will be responsible for the oligonucleotide synthesis, purification, desalting, and analysis to support the process development of guide RNA production in various scales. This position will also support therapeutic programs in multiple disease areas in R&D department. Prior experience in oligonucleotide synthesis, purification, and characterization is desired.
Responsibilities
- Implement and optimize the process for oligonucleotide synthesis, purification, and desalting
- Characterize oligonucleotides for purity determination and impurity profiling
- Manage lab instruments and reagent inventory
- Maintenance of an accurate and up-to-date record of experiments and results in the form of ELN entries and written reports
- Communication of key findings in group and cross-functional team meetings
- Contribution to regulatory and IP filings
- Performance of laboratory work in safe, efficient manner that ensures a safe working environment for all colleagues
Minimum Qualifications
- MS degree in Chemistry, Chemical Engineering, Biochemistry, Bioengineering, Pharmaceutical Sciences or related field, or BS degree in a similar field and 3+ years of relevant experience
- Strong hands-on skills, organizational skills, and attention to details in laboratory benchwork
- Fundamental knowledge in organic chemistry, biochemistry, and analytical chemistry
- A learner’s mindset with a commitment to personal growth and a drive to broaden technical skills and scientific knowledge
- Willingness to invest in communications and scientific engagements with colleagues
- Ability to think strategically, efficiently manage time and workflows, and work both independently and collaboratively in a cross-functional team environment
- Ability to thrive in a fast-paced, dynamic work environment
Preferred Qualifications
- Hands-on experience with Oligonucleotide Chemistry and nucleic acid biochemistry
- Prior experience with oligonucleotide synthesis and purification
- Working experience with analytical techniques (such as UPLC, LC-MS) and data interpretation
Competencies
- Collaborative – Openness, One Team
- Undaunted – Fearless, Can-do attitude
- Results Orientation – Delivering progress toward our mission. Sense of urgency in solving problems.
- Entrepreneurial Spirit – Proactive. Ownership mindset.
CRISPR Therapeutics believes in fostering a dynamic workplace that balances remote work flexibility with the benefits of in-person interactions. Our employees work at least three days on-site, creating a collaborative work environment, where we cultivate mentorship opportunities, increase cross-functional communication and offer opportunities for our employees to connect. Certain lab based and manufacturing positions are located fully on-site.
CRISPR Therapeutics, Inc. is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law.
To view our Privacy Statement, please click the following link: http://www.crisprtx.com/about-us/privacy-policy
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