Address
Form of workLocation: Chicago, IL
Hospital: RUSH University Medical Center
Department: Neurological Sciences-Res Adm
Work Type: Full Time (Total FTE between 0. 9 and 1. 0)
Shift: Shift 1
Work Schedule: 8 Hr (8:00:00 AM - 4:30:00 PM)
Summary:
The Research Associate will design and perform complex scientific research experiments. This person will be involved in creating symptoms and pathology in mice similar to multiple sclerosis. The position will utilize knowledge of proteomics, molecular biology, neurobiology, cell biology, biochemistry, and animal brain surgery. This person will troubleshoot and evaluate data, and prepare manuscripts based on experimental results. The work requires the application of highly specialized knowledge of neuroinflammation and neurodegeneration. Some of the related techniques that may be applied in the research to be conducted will include: microinjection, mass spectrometry, high-throughput screening, mammalian cell culture, cell transfection assays, flow cytometry (FACS), immunoprecipitation/Western blots. He will be also involved in training one PhD student. Exemplifies the Rush mission, vision and values and acts in accordance with Rush policies and procedures.
Responsibilities:
Mentoring a PhD student
Maintaining and breeding transgenic mice
Establishing a mouse model of multiple sclerosis by tail-vein injection of autoreactive T cells
Creating a new mouse model of multiple sclerosis by RANTES intoxication
Intranasal, intraperitoneal and oral treatment of mouse models of multiple sclerosis by different drugs
Monitoring locomotor activities of mouse models of multiple sclerosis before and after drug treatment
Examining the levels of different genes and protein in the brain
Culturing different brain cells
Assaying activities of different T lymphocytes
Animal transcranial perfusion and histology.
Performing immunohistochemistry and confocal/bright field microscopy
Statistical analysis of data analysis
Prepare abstracts and manuscripts
Write grants
Other information:
Required Job Qualifications:
Ph.D. with expertise in neuroinflammation and neurodegeneration focusing on multiple sclerosis
T cell activation, tail vein injection, student mentoring, and manuscript writing
Ability to work for 8 hours daily in the lab.
Disclaimer: The above is intended to describe the general content of and requirements for the performance of this job. It is not to be construed as an exhaustive statement of duties, responsibilities or requirements.
Rush is an equal opportunity employer. We evaluate qualified applicants without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, and other legally protected characteristics.
