Assistant Research Professor Of Pathology & Laboratory Medicine

The Indiana University School of Medicine has an exciting opportunity of an Assistant Research Professor within the team led by Drs. Anita Bellail, and Chunhai “Charlie” Hao, in Department of Pathology & Laboratory Medicine for protein structure-guided drug discovery, which focuses now on anticancer and antiaging drugs.
Our team investigates targeted protein degradation for the discovery of small molecule degraders. The team has recently reported the first small molecule degraders of SUMO1 protein as novel anticancer drugs (Bellail et al. Science Translational Medicine 2021, 13:e12947). The team has submitted a manuscript on the discovery of small-molecule degraders of amyloid procurer protein (APP) for treatment of Alzheimer’s disease. The team is currently working on Cryo-EM and NMR structures of molecule degrader-induced protein complex and thus developing the structure-guided and AI-powered drug design.

Primary Job Duties and Responsibilities:

• Experimental design, execution, interpretation, and publication

The position is funded by NIH and other foundation grants and salary is based on the IUSM standards on the experience of the applicants. The position is available for an initial appointment of one year, renewable for subsequent years.
As the nation’s largest medical school, IUSM is committed to being an institution that not only reflects the diversity of the learners we teach and the patient populations we serve, but also pursues the values of diversity, equity and inclusion that inform academic excellence. We desire candidates who enhance our representational diversity, as well as those whose work contributes to equitable and inclusive learning and working environments for our students, staff, and faculty. IUSM strives to take an anti-racist stance, regularly evaluating and updating its policies, procedures, and practices to confer equitable opportunities for contribution and advancement for all members of our community. We invite individuals who will join us in our mission to advance racial equity to transform health and wellbeing for all throughout the state of Indiana.
Indianapolis is the capital and most populous city in the State of Indiana. It is growing economically thanks to a strong corporate base anchored by the life sciences. Indiana is home to one of the largest concentrations of health sciences companies in the nation. Indianapolis has a sophisticated blend of charm and culture with a wonderful balance of business and leisure. The growing residential base is supported by rich amenities and quality of life – the city possesses a variety of professional sports, arts venues and outdoor recreation areas. Residents of this dynamic city, and surrounding suburbs, enjoy leading educational systems and top-ranked universities, paired with a diverse population. Indianapolis International Airport is a top-ranked international airport, being named “Best Airport in North America” by Airports Council International for many years. For additional information on life in Indy: https://faculty.medicine.iu.edu/relocation

Ph.D. degree in the field of structural biology is required.
Minimum Qualifications: