Temporary Research Associate - Lead Identification Group, Antisense Drug Discovery

Ionis Pharmaceuticals, Inc., is headquartered in Carlsbad, California, with offices in Boston, Massachusetts, and Dublin, Ireland. For more than 30 years, Ionis has been the leader in RNA-targeted therapy, pioneering new markets and changing standards of care with our novel antisense technology. Ionis currently has three marketed medicines and a premier late-stage pipeline highlighted by industry-leading cardiovascular and neurological franchises. Our scientific innovation began and continues with the knowledge that sick people depend on us, which fuels our vision to become the undisputed leader in genetic medicine, utilizing a multi-platform approach to discover, develop and deliver life-transforming therapies.
As the first company to fully harness the power of RNA technology for human therapeutics, Ionis' platform continues to revolutionize Drug Discovery and transform lives for patients with unmet needs. We are building upon our innovative research and drug development excellence to provide greater value to patients, and we are well positioned financially to deliver on our strategic goals.
Ionis is a challenging, motivating and rewarding environment designed to foster innovation and scientific excellence. Our success is a direct result of our outstanding employees. We are interested in bringing together a diverse group of individuals with different skill sets and perspectives into this creative environment to be part of a productive and inclusive team. While acknowledging people are actively engaged in hybrid/remote work, we continue to invest time, money, and energy into making our workplace locations a place where our culture and employees can thrive. We believe engaging on a day-to-day basis, in person, builds solid and lasting relationships, and contributes positively to our culture and innovation. From the heart of our stunning Carlsbad campus, we aim to provide a central connection point for all our employees. These facilities give us the opportunity to connect cross-functionally, collaborate and to build on the success of our business as we continue to grow. Join us and experience our unique culture while you develop and expand your career.
TEMPORARY RESEARCH ASSOCIATE - LEAD IDENTIFICATION GROUP, ANTISENSE DRUG DISCOVERY
SUMMARY:
We are seeking a highly motivated and outstanding individual to join the Antisense Lead Identification group as a Temporary Research Associate (initial 6 month contract). The selected candidate will work within a fast-paced, interactive, and innovative research team on antisense oligonucleotide in vitro screening for Lead Identification and development. The successful candidate is expected to be self-motivated and able to work productively in a team environment as well as independently. The applicant should have a strong desire to apply their biological sciences background in an automated high-throughput environment. This position is an onsite laboratory research position which will require the successful candidate to be onsite. We cultivate a work environment with many opportunities to learn in R&D and encourage all highly motivated candidates to apply.
RESPONSIBILITIES:

• Supporting Drug Discovery research through antisense oligonucleotide (ASO) activity characterization
• Executing Lead Identification screening for ASOs and siRNA compounds
• Maintaining mammalian cell cultures for cell-based assays and transfection
• Applying molecular biology techniques including transfection, RNA processing, and RT-qPCR
• Analyzing complex/large data sets and troubleshooting results
• Assisting Senor Scientists in experiment execution, maintaining instruments, organizing and managing samples and reagents
• Operating and troubleshooting liquid handler automation and robotics for high throughput cell-based assays and RT-qPCR (96-well and 384-well format), which includes use of the Hamilton STAR, Minitrak, and Janus instruments

REQUIREMENTS:

• A Bachelor's degree (B.S.) in Biology or a related field with 1-4 years of laboratory experience.
• Hands-on experience with mammalian cell culture (cell lines and/or primary cells).
• Experience with molecular biology techniques such as nucleic acid purification, RT-qPCR and cell-based assays.
• Desire to work in an environment with high throughput automation
• Experience with large sample management and data tracking (xls and structured datasets)
• Strong attention to detail.
• Demonstrated ability to work independently and productively.
• Strong organization, effective time management, and project prioritization skills
  
  • Ability to be successful in an intense work environment
  • Ability to be flexible as workload and priorities demand

For more information about Ionis and to apply for this position, please visit our website, www.ionispharma.com. Reference Requisition #TEMPO003244
The hourly pay scale for this position is $34.41/hour to $50.35/hour
Temp Research Associate pay scale is $34.41/hour - 39.66/hour
Temp Research Associate II pay scale is 39.46/hour - $45.70/hour
Temp Senior Research Associate pay scale is $43.27/hour - $50.35/hour
NO PHONE CALLS PLEASE. PRINCIPALS ONLY.
Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.