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Form of work About City of Hope
City of Hope's mission is to deliver the cures of tomorrow to the people who need them today. Founded in 1913, City of Hope has grown into one of the largest cancer research and treatment organizations in the U.S. and one of the leading research centers for diabetes and other life-threatening illnesses. City of Hope research has been the basis for numerous breakthrough cancer medicines , as well as human synthetic insulin and monoclonal antibodies. With an independent, National Cancer Institute-designated comprehensive cancer center at its core, City of Hope brings a uniquely integrated model to patients spanning cancer care, research and development, academics and training, and innovation initiatives. City of Hope's growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and treatment facilities in Atlanta, Chicago and Phoenix. City of Hope's affiliated group of organizations includes Translational Genomics Research Institute and AccessHopeTM . For more information about City of Hope, follow us on Facebook , Twitter , YouTube , Instagram and LinkedIn .
City of Hope's commitment to Diversity, Equity and Inclusion
We believe diversity, equity and inclusion is key in serving our mission to provide compassionate patient care, drive innovative discovery, and advance vital education focused on eliminating cancer and diabetes in all of our communities. Our commitment to Diversity, Equity and Inclusion ensures we bring the full range of skills, perspectives, cultural backgrounds and experiences to our work and that our teams align with the people we serve in order to build trust and understanding. We are dedicated to fostering a community that embraces diversity - in ideas, backgrounds and perspectives; this is reflected in our work and represented in our people.
Position Summary and Key Responsibilities
Dr. Yanhong Shi's laboratory is looking for a highly motivated Staff Scientist to conduct cutting-edge Stem Cell Research projects in the Department of Neurodegenerative Diseases of the Beckman Research Institute of City of Hope located in the county of Los Angeles, California.
The Shi laboratory is well known for Stem Cell Research using the human induced pluripotent Stem Cell (iPSC) platform. The group has pioneered Stem Cell-based modeling of various neurological disorders and is at the forefront of cell therapy development for Canavan disease. The Shi laboratory is also among the first to demonstrate critical roles of RNA modifications in glioblastoma tumorigenesis. The Shi laboratory has published extensively in these areas, and some of the recently published papers include: Advanced Science 2020, 2021, 2023; Cell Reports 2016, 2017, 2023; Cell Reports Medicine 2020; Cell Stem Cell 2018, 2021, 2023; Nature Cancer 2021; Nature Communications 2016, 2016, 2019; Nature Reviews Drug Discovery 2017; Trends in Pharmacological Sciences (Cell Press) 2022; and Trends in Molecular Medicine (Cell Press) 2023.
(see the publication list here: https://pubmed.ncbi.nlm.nih.gov/?term=yanhong shi and Duarte&sort=date).
The Shi laboratory has established protocols for differentiating human iPSCs into a variety of cell types, including brain cells, blood cells, and organoids, and has developed cellular models and cell therapeutic candidates for diseases such as Alzheimer's disease, Canavan disease, and glioblastoma. The Shi laboratory has well-established experimental platforms and sufficient funds for candidates who are interested in conducting first-class science.
Basic education, experience and skills required for consideration:
• Candidates should have an advanced degree (Ph.D., M.D., or equivalent) in biomedical science, with experience in original research discovery and publication, project management, and/or grant proposal preparation.
• The Staff Scientist will lead projects on human iPSC-based disease modeling and/or therapeutic development and is expected to write grant proposals/progress reports and prepare high-quality manuscripts for publication.
• Experience in human iPSC culture, CRISPR/Cas9-mediated gene editing, and differentiation of human iPSCs into neural and/or immune cells and organoids is a plus. Strong molecular biology background is preferred.
• Candidates should be highly motivated, have excellent writing, interpersonal, and multi-tasking skills.
Additional Information:
• For more information about Dr. Yanhong Shi's lab, please visit here .
• We welcome highly motivated scientists to join us. The Staff Scientist position is well supported by salary and fringe benefits, which include health insurance and retirement plans.
• The estimated pay scale represents the typical [salary/hourly] range City of Hope reasonably expects to pay for this position, with offers determined based on several factors which may include, but not be limited to, the candidate's experience, expertise, skills, education, job scope, training, internal equity, geography/market, etc. This pay scale is subject to change from time to time.
• As a condition of employment, City of Hope requires staff to comply with all state and federal vaccination mandates.
City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.
City of Hope's mission is to deliver the cures of tomorrow to the people who need them today. Founded in 1913, City of Hope has grown into one of the largest cancer research and treatment organizations in the U.S. and one of the leading research centers for diabetes and other life-threatening illnesses. City of Hope research has been the basis for numerous breakthrough cancer medicines , as well as human synthetic insulin and monoclonal antibodies. With an independent, National Cancer Institute-designated comprehensive cancer center at its core, City of Hope brings a uniquely integrated model to patients spanning cancer care, research and development, academics and training, and innovation initiatives. City of Hope's growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and treatment facilities in Atlanta, Chicago and Phoenix. City of Hope's affiliated group of organizations includes Translational Genomics Research Institute and AccessHopeTM . For more information about City of Hope, follow us on Facebook , Twitter , YouTube , Instagram and LinkedIn .
City of Hope's commitment to Diversity, Equity and Inclusion
We believe diversity, equity and inclusion is key in serving our mission to provide compassionate patient care, drive innovative discovery, and advance vital education focused on eliminating cancer and diabetes in all of our communities. Our commitment to Diversity, Equity and Inclusion ensures we bring the full range of skills, perspectives, cultural backgrounds and experiences to our work and that our teams align with the people we serve in order to build trust and understanding. We are dedicated to fostering a community that embraces diversity - in ideas, backgrounds and perspectives; this is reflected in our work and represented in our people.
Position Summary and Key Responsibilities
Dr. Yanhong Shi's laboratory is looking for a highly motivated Staff Scientist to conduct cutting-edge Stem Cell Research projects in the Department of Neurodegenerative Diseases of the Beckman Research Institute of City of Hope located in the county of Los Angeles, California.
The Shi laboratory is well known for Stem Cell Research using the human induced pluripotent Stem Cell (iPSC) platform. The group has pioneered Stem Cell-based modeling of various neurological disorders and is at the forefront of cell therapy development for Canavan disease. The Shi laboratory is also among the first to demonstrate critical roles of RNA modifications in glioblastoma tumorigenesis. The Shi laboratory has published extensively in these areas, and some of the recently published papers include: Advanced Science 2020, 2021, 2023; Cell Reports 2016, 2017, 2023; Cell Reports Medicine 2020; Cell Stem Cell 2018, 2021, 2023; Nature Cancer 2021; Nature Communications 2016, 2016, 2019; Nature Reviews Drug Discovery 2017; Trends in Pharmacological Sciences (Cell Press) 2022; and Trends in Molecular Medicine (Cell Press) 2023.
(see the publication list here: https://pubmed.ncbi.nlm.nih.gov/?term=yanhong shi and Duarte&sort=date).
The Shi laboratory has established protocols for differentiating human iPSCs into a variety of cell types, including brain cells, blood cells, and organoids, and has developed cellular models and cell therapeutic candidates for diseases such as Alzheimer's disease, Canavan disease, and glioblastoma. The Shi laboratory has well-established experimental platforms and sufficient funds for candidates who are interested in conducting first-class science.
Basic education, experience and skills required for consideration:
• Candidates should have an advanced degree (Ph.D., M.D., or equivalent) in biomedical science, with experience in original research discovery and publication, project management, and/or grant proposal preparation.
• The Staff Scientist will lead projects on human iPSC-based disease modeling and/or therapeutic development and is expected to write grant proposals/progress reports and prepare high-quality manuscripts for publication.
• Experience in human iPSC culture, CRISPR/Cas9-mediated gene editing, and differentiation of human iPSCs into neural and/or immune cells and organoids is a plus. Strong molecular biology background is preferred.
• Candidates should be highly motivated, have excellent writing, interpersonal, and multi-tasking skills.
Additional Information:
• For more information about Dr. Yanhong Shi's lab, please visit here .
• We welcome highly motivated scientists to join us. The Staff Scientist position is well supported by salary and fringe benefits, which include health insurance and retirement plans.
• The estimated pay scale represents the typical [salary/hourly] range City of Hope reasonably expects to pay for this position, with offers determined based on several factors which may include, but not be limited to, the candidate's experience, expertise, skills, education, job scope, training, internal equity, geography/market, etc. This pay scale is subject to change from time to time.
• As a condition of employment, City of Hope requires staff to comply with all state and federal vaccination mandates.
City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.
