AddressDescription
Description:
As a Senior Research Associate, you will work with a team of scientists and Research Associates to advance our gene editing technologies, enabling the discovery of new therapeutics, and improving their function so they can be safely and effectively delivered to patients. You will primarily be performing tissue culture-based assays to evaluate gene modifications as measured by NGS and flow cytometry.
Primary Responsibilities:
• Support all tissue culture needed to measure gene editing therapeutics, using both primary and immortalized cell lines
• Perform transfections, including with LNPs, transductions and electroporations of nucleic acids at 96-well scale
• Perform tissue culture assays for measuring gene modification outcomes via NGS and flow cytometry
• Utilize and improve methods for high-throughput tissue culture experiments, including VIAFLO pipettes and liquid-handling robots
• Produce RNA, LNP and virus research articles
Skills:
molecular biology, mammalian cell culture, research, cell culture, tissue culture, cell line, Assay, assay development, next generation sequencing, sequencing, crispr, protein engineering, python, rna engineering, flow cytometry, pipetting, liquid handling, sop
Qualifications:
• A minimum of 3 years of experience maintaining and transforming multiple immortalized cell lines, and primary cell lines
• Experience with multiple transfection and transduction approaches: ie lipid-based transformations, lonza nucleofectors, and AAV and other viral transductions
• Capable of running and maintaining cytometer and/or high-content imaging instruments, along with preparing samples to run on these instruments
• Experience working with, and developing SOPs for, tissue culture automation tools
Education / Experience:
• Bachelor's degree in Molecular Biology or related field and 6+ years of experience in the biotech industry, or Master's degree in Molecular Biology or related
field and 4+ years in the biotech industry.
Experience Level:
Expert Level
About Actalent
Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 30,000 consultants and more than 4,500 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500.
Diversity, Equity & Inclusion
At Actalent, diversity and inclusion are a bridge towards the equity and success of our people. DE&I are embedded into our culture through:
- Hiring diverse talent
- Maintaining an inclusive environment through persistent self-reflection
- Building a culture of care, engagement, and recognition with clear outcomes
- Ensuring growth opportunities for our people
The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.
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