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Form of workWho we are...
Cell Signaling Technology (CST) is a different kind of life sciences company, one founded, owned, and run by active research scientists, with the highest standards of product and service quality, technological innovation, and scientific rigor for over 20 years. We consistently provide fellow scientists around the globe with best-in-class products and services to fuel their quests for discovery.
Helping researchers find new solutions is our main mission every day, but it's not our only mission. We're also dedicated to helping identify solutions to other problems facing our world. We believe that all businesses must be responsible and work in partnership with local communities, while seeking to minimize their environmental impact. That's why we joined 1% for the Planet as its first life science member and have committed to achieving net-zero emissions by 2029.
The role...
The molecular biology team plays a vital role in supporting the CST monoclonal antibody discovery platform. The successful candidate will be responsible for designing and cloning expression constructs to support the company's antibody discovery pipeline. Qualified candidates will be able to independently design and build expression constructs using their expertise in DNA sequence analysis, PCR, Molecular Cloning, and Plasmid production. They will also utilize collaborative teamwork in a fast-paced laboratory setting to deliver sequence-verified plasmids to the end users.
You'll have the opportunity to...
- Design and build plasmids for the overexpression of proteins in mammalian cells
- Use DNA sequence analysis for plasmid verification
- Engineer proteins with the addition of detection tags, introduce amino acid substitutions, build protein fusions, etc.
- Prepare plasmid preps for delivery to user groups within CST in a timely manner
- Maintain accurate physical inventories of plasmid stocks
- Maintain accurate and complete laboratory documentation, including hard copy notebooks and CST electronic records
- Adhere to standard operating procedures in lab operations and safety in accordance with Quality Management Systems
- Seek out technological opportunities that will improve the quality and efficiency of the pipeline.
Who you are and what you bring to the team...
- Bachelors in Biological Sciences (Biochemistry, Biotechnology, or related discipline) and 4-6 years of lab experience or Master's degree in Biological Sciences or related degree with 1-2 years of lab experience.
- Hands-on experience designing and cloning protein expression constructs.
- Molecular cloning techniques (e.g., PCR, Restriction enzymes, GoldenGate Assembly, Gibson Assembly)
- Plasmid DNA purification (e.g., miniprep and large scale)
- Plasmid QC (e.g., gel electrophoresis, quantitation, normalization)
- DNA sequence analysis software and plasmid map construction (e.g., MacVector, SnapGene, etc.)
- Proven ability to work in a high-throughput and fast-paced environment
- Exquisite attention to detail and organizational skills
- Strong verbal and written communication skills and ability to thrive in a team environment
Ideally, you have...
- Experience with automation platforms (e.g., Hamilton Robotics)
- Strong written and oral communication skills
- Proven experience working successfully in a team environment
- Experience with Google Suite (or Microsoft Word, Excel, PowerPoint), LIMS, and JIRA
- Familiarity with antibodies is a plus
What we offer....
At Cell Signaling Technology (CST) we recognize that people will always be our most important asset. Providing a safe, inclusive, and stimulating working environment that understands the importance of diversity, human dignity, and meaningful work is as important as establishing company policies that incorporate excellent health insurance and pay benefits. We recognize that the development of people is the key to their happiness and thus ensure every employee has impactful discussions with their manager and develops actionable performance and professional development plans. Lastly, we are committed to engaging and supporting our employees in committees and philanthropy that benefit their local communities and environment through community investment programs.
Benefits
- Medical (BCBS) and Dental (Delta Dental) plans paid at 90%
- Vision Insurance
- Life Insurance, Short and Long Term Disability
- Flexible Spending accounts
- 401(k) Plan with 6% match
- Tuition Reimbursement
- Generous PTO package
- Pet Insurance
- Employee Assistance Program
- Onsite Subsidized Cafeteria
- Free Parking
Cell Signaling Technology (CST) is committed to providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, status as a veteran or as a member of the military or status in any group protected by applicable federal or state laws.
AGENCIES
All resumes submitted by search firms/employment agencies to any employee at Cell Signaling Technology (CST) via email, the internet or in any form and/or method will be deemed the sole property of CST, unless CST engaged such search firms/employment agencies for this position and a valid agreement with CST is in place. In the event a candidate who was submitted outside of the CST agency engagement process is hired, no fee or payment of any kind will be paid.
Physical Conditions/Physical Requirements
- Laboratory work environment
- The work area can be filled with collaborative discussion
- The work area may have noise from equipment (refrigerator, freezer, etc.)
- May work with hazardous chemicals and materials
- Ability to lift at least 20 pounds
- Work environment conditions consist of both sitting and standing throughout the day
