Senior Associate Scientist, Ipsc Biology

The Role: 

The Genome Editing group is looking for a Senior Associate Scientist with expertise in iPSC biology to help expand our therapeutic capabilities and continue to improve our technology discovery platform. The successful candidate will have a strong background in iPSC culture, experience with genome editing, and expertise engineering cellular models. We are interested in curious, enthusiastic, competent, and self-motivated individuals to work in our company. A willingness to embrace our cultural values will be critical for success in this role. This is an exciting opportunity to help build a successful therapeutics company from an early stage.

Here’s What You’ll Do: 

• Assist standardizing protocols for the differentiation of iPSCs into specific cell types.
• Optimize methods for introducing Life Edit genome editing systems into pluripotent cells and their progeny.
• Establish rigorous standards and quality control measures for iPSC culture and differentiation
• Work closely with cross-functional teams and coordinate with team members to align project objectives with experimental approaches and timelines.
• Analyze and interpret data ensuring clear documentation of methodologies and outcomes.
• Prepare detailed reports and presentations for internal and external partners to communicate progress in line with project schedules.
• Assist in mentoring and training research associates and coordinating the day-to-day operations.
• Follow advancements in the field of gene editing and gene therapy published in the literature and presented at conferences.

Requirements: 

• Master’s degree or a bachelor’s degree with 3+ years of experience in Biochemistry, Cell biology, Molecular biology, Neuroscience, or a related field.
• Expertise in culturing and characterizing pluripotent cells.
• Expertise in differentiating pluripotent cells into different cell types.
• Ability to design, plan, and implement pluripotent cell differentiation techniques.
• Expertise in molecular and biochemical techniques including DNA/RNA extraction, PCR, qPCR, qRT-PCR, NGS, WB, IF, ELISA, and Flow Cytometry
• Direct experience in genome editing mammalian cells is highly preferred.
• Outstanding communication skills (verbal and written).
• Passion and ability to learn new concepts and skills.
• Ability to collaborate in a team-oriented environment.
• Occasional weekend work is required.

Why join Life Edit and the ElevateBio ecosystem?

Life Edit Therapeutics is an integrated subsidiary of ElevateBio, a technology-driven cell and gene therapy company that is accelerating access to the cutting-edge technologies and expertise that can change the future of medicine. Our integrated model combines multiple R&D technology platforms – including Life Edit gene editing – and cGMP manufacturing to power the discovery and development of advanced therapeutics. Our ecosystem is designed to enhance speed, delivery, and probability of success to change patient lives.

Life Edit is an integral part of ElevateBio’s ecosystem of platform technologies and is pioneering focused next-generation gene editing technologies and therapeutics. Located in Durham, NC, members of Life Edit work closely with the ElevateBio Research and Development and BaseCamp manufacturing teams in Waltham, MA. Life Edit is advancing therapeutic programs in collaboration with industry partners while building its own internal pipeline of gene editing therapies. We are looking for a unique individual who can continue to lead the cultural development of Life Edit and build on its momentum as an integral part of the ElevateBio ecosystem.

Our Mission:
To power the creation of life-transforming cell and gene therapies, at a speed the world deserves.

Our Vision:
We seek to be the world’s most indispensable cell and gene therapy technology company, redefining how companies operate, how products are created and how disease is treated.

ElevateBio is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. ElevateBio will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.