Scientist - Sr Staff

We are seeking an experienced and innovative Molecular Diagnostics Research Scientist II with a strong background in Next-Generation Sequencing (NGS) to join our dynamic R&D team. This role focuses on the development, optimization, and validation of NGS-based assays for clinical diagnostics applications. The ideal candidate will have a deep understanding of molecular biology, bioinformatics, and clinical assay development processes. This position involves close collaboration with cross-functional teams to drive projects from conception through to clinical implementation.

• Design, develop, and validate NGS-based assays for the detection, quantification, and characterization of nucleic acid targets in a clinical diagnostic setting.
• Optimize protocols for DNA/RNA extraction, library preparation, sequencing, and data analysis to improve assay performance and efficiency.
• Conduct rigorous analytical validation studies to establish the performance characteristics of new assays, including sensitivity, specificity, accuracy, precision, and reproducibility.
• Collaborate with bioinformatics scientists to develop and refine data analysis pipelines and ensure the accurate interpretation of sequencing results.
• Stay abreast of technological advancements and emerging trends in NGS and molecular diagnostics to identify opportunities for innovation and improvement.
• Contribute to the preparation of technical documentation, including standard operating procedures (SOPs), validation reports, and regulatory submissions.
• Present findings and progress reports to internal teams, management, and external stakeholders.
• Mentor junior scientists and technicians, providing guidance and support in experimental design, data analysis, and troubleshooting.

• PhD in Molecular Biology, Genetics, Biochemistry, or a related field, with a minimum of 2 years of post-doctoral experience in a relevant area. Alternatively, a Master’s degree with 5+ years of relevant industry experience.
• Proven expertise in NGS technologies and their application in molecular diagnostics, including hands-on experience with assay development and validation.
• Strong background in molecular biology techniques such as PCR, qPCR, DNA/RNA isolation, and library preparation.
• Experience with bioinformatics tools and software for NGS data analysis.
• Familiarity with regulatory requirements and quality standards relevant to clinical diagnostics, including CLIA, CAP, and FDA guidelines.
• Excellent problem-solving skills and the ability to work independently as well as part of a team.
• Strong communication skills, both written and verbal, with the ability to present complex data to a variety of audiences.

Quest Diagnostics is an equal employment opportunity employer. Our policy is to recruit, hire and promote qualified individuals without regard to race, color, religion, sex, age, national origin, disability, veteran status, sexual orientation, gender identity, or any other status protected by state or local law. Quest Diagnostics observes minimum age requirements established by federal, state and/or local laws, and will ask an applicant for verification when deemed necessary.