Scientist, Gene Therapy Bioanalytical Sciences

CSL Behring is a global biotechnology leader, guided by a promise to save and improve lives. Millions of people around the world are living with rare and serious medical conditions. CSL Behring is committed to delivering medicines that improve their lives.

With operations in 35+ nations and ~ 30,000 employees worldwide, CSL is inspired to develop and deliver a broad range of lifesaving therapies to treat disorders such as hemophilia and primary immune deficiencies, and vaccines to prevent influenza. Our therapies are also used in cardiac surgery, organ transplantation and burn treatment. CSL is the parent company of CSL Behring, CSL Plasma, CSL Seqirus and CSL Vifor. CSL Behring is a global leader in the protein biotherapeutics industry, focused on bringing to market biotherapies used to treat serious and often rare conditions.

Could you be our next Scientist, Gene Therapy Bioanalytical Sciences? This position is located in our Pasadena CA office. You will report to the Senior Scientist, Bioanalytics

You will be responsible for the development and qualification of cellular- and molecular- based potency assays suitable for release testing and characterization of cell and Gene Therapy products, recombinant and plasma-derived proteins and vaccines.

THE ROLE

• Develop and qualify analytical methods for product release testing and characterization, integrating multiple analytical platforms to assess biological function and product potency.
• Provide analytical support for research and product development activities, including preclinical studies and process development as well as GMP product testing.
• Draft assay development plans and reports as well as qualification protocols and reports.
• Transfer assays internally and externally where required.
• Maintain laboratory quality systems and records of analytical results

REQUIREMENTS

• B.S. in a Biomedical discipline. Advanced degree is preferred.
• At least 2 years’ experience in biomedical research at an academic research institution or biotechnology company.
• Well-versed in HSC Biology and hematopoiesis. Background in Gene Therapy, gene editing, and/or cell therapy preferred.
• Proficient in cell isolation, culture, expansion, differentiation, and CFU analysis.
• Well-versed in DNA/RNA isolation and characterization (multiplex ddPCR, qPCR) and molecular biology methods.
• Experience with multicolor flow cytometry and immunophenotyping.
• Experience with cell function assays (phagocytosis, chemotaxis, proliferation, differentiation)
• Familiarity with immunology and ELISA, MSD, and/or Olink platforms a plus.
• Experience in assay development and phase-appropriate assay qualification.
• Experience authoring SOPs and work instructions.
• Effective time management skills and ability to work/lead in a cross-functional, multidisciplinary team environment.
• Working knowledge of GMP/GLP and quality control principles

#LI-Onsite

The expected base salary range for this position at hiring is $95,000-125,000 Please note this salary range reflects the minimum and maximum base pay that CSL expects to pay for this position at the listed location as of the time of this posting. Individual base salary for a successful candidate is determined by qualifications, skill level, experience, competencies and other relevant factors. In addition to base salary, total compensation for this role may also include incentive compensation

CSL employees that work at least 30 hours per week are eligible for benefits effective day 1. We are committed to the wellbeing of our employees and their loved ones. CSL offers resources and benefits, from health care to financial protection, so you can focus on doing work that matters. Our benefits are designed to support the needs of our employees at every stage of their life. Whether you are considering starting a family, need help paying for emergency back up care or summer camp, looking for mental health resources, planning for your financial future, or supporting your favorite charity with a matching contribution, CSL has many benefits to help achieve your goals.

Please take the time to review our benefits site to see what’s available to you as a CSL employee.

CSL Behring is a global leader in developing and delivering high-quality medicines that treat people with rare and serious diseases. Our treatments offer promise for people in more than 100 countries living with conditions in the immunology, hematology, cardiovascular and metabolic, respiratory, and transplant therapeutic areas. Learn more about CSL Behring.

As a global organization with employees in 35+ countries, CSL embraces diversity and inclusion. Learn more about Diversity & Inclusion at CSL.