Scientist, Biotherapeutics

Seismic Therapeutic, a biotechnology startup focused on the intersection of structure, protein engineering, machine learning and immunology, is seeking an exceptional and enthusiastic Scientist to help drive novel immunotherapy programs. The successful candidate will contribute to Seismic’s mission to develop novel immunotherapies and create an IMPACT on diseases of the adaptive immune system by expressing, purifying, and characterizing therapeutic molecules.

About Seismic: Seismic is determined to help patients with unmet need by integrating machine learning, structural biology, protein engineering, and translational immunology to generate clinic-ready drugs. At our core, we are focused on phenomenal science, supportive culture, a superstar team, meritocracy, and patient-centric goals. Seismic has the tools, skills, ideas and people to make this a reality. Success will be the discovery and development of effective therapies for patients in need, and we invite you to become a part of that.

Who You Are:

• A rigorous scientist with a background in biochemistry and protein analytics.
• A person with a keen eye for detail, exceptional time management skills and an organized approach.
• A team-player who thrives in a scientifically diverse, fast-paced, collaborative start-up environment.
• Eager to contribute to shaping an open, inclusive, and rigorous company culture by embracing teamwork, creativity, and a can-do attitude; lead by example to create and sustain an intellectually rich and dynamic work environment that is supportive and inclusive.
• Passionate about improving patients’ lives.

Responsibilities:

• Express and purify therapeutic molecules across multiple scales in various systems.
• Characterize molecules using a variety of analytical techniques to assess purity, stability, and other biochemical and biophysical properties.
• Develop and execute high-throughput assays to assess the feasibility of early therapeutic candidates.
• Collaborate and communicate in a matrixed environment.
• Detailed documentation, analysis, and interpretation of experiments.

Required Qualifications:

• PhD in biochemistry/biophysics, biological/chemical engineering, or a related discipline with 0-2 years experience
• Experience in protein expression, purification using a variety of techniques (affinity, SEC, IEX, mixed-mode, etc.), and analytical characterization.
• Experience in diverse biochemical and biophysical techniques such as DSF, DLS, IEF is a plus.
• Experience working with bispecific and non-traditional antibody formats is a plus.

As a member of our diverse and growing team, you’ll help shape Seismic into a company that takes its scientific mission seriously while providing a positive and supportive workplace environment and culture. With your insights, passion and talent - we’ll bring novel therapeutics to the patients who need them the most.

Seismic Therapeutics is an equal opportunity employer. We will not tolerate discrimination on the basis of race, color, national origin, sex, sexual orientation, gender identity, religion, age, disability, veteran's status, pregnancy, genetic information or on any basis prohibited by federal, state or local law.