Research Assistant Ii - In Vivo Pharmacology

This is an exciting opportunity to join JAX as a Research Assistant for In Vivo Pharmacology services and start or pursue a career in the preclinical drug development industry!
The In Vivo services group (https://www.jax.org/jax-mice-and-services/in-vivo-pharmacology) is external-facing and assists industry and academic clients in their pre-clinical drug development program, by conducting efficacy studies on carefully baselined and validated mouse models for a variety of neurobiology indications. These include peripheral nerves and muscles diseases like ALS, SMA, or Duchenne muscular dystrophy, autism-spectrum disorders and lysosomal storage diseases.
The Research Assistant II works under minimal supervision of a Project Manager or Study Director. The successful applicant in this role has learned the phenotypes, protocols and data analyses relevant to the disease models they work on, and can apply and interpret theoretical knowledge necessary to conduct the studies. The range of duties includes, but is not limited to: project planning, developing methodology, conducting procedures, modifying procedures as needed, data collection and analysis, contributing to client updates and study reports with the Study Director. Effective mental concentration, visual attention and manipulative skills for live animals, histology samples and molecular biology reagents are critical for the position. The Research Assistant II may assist in training others within or external to their assigned work area. Incumbents may be required to occasionally work flexible shifts that may include evenings, week-ends and/or holidays depending on the demands of the study and/or laboratory operations.
Key Responsibilities & Essential Functions:

• Execution of drug formulation protocols, drug administration, phenotypic testing (eg. electromyography, or locomotor and behavioral testing), wet lab molecular biology and biochemistry experiments (eg qPCR, protein analyses by Western Blot, computer-assisted image analyses, FACS).
• Identification and reporting of problems in protocols and results of studies, troubleshooting and analyzes of variations; modification, refinement or adaptation of techniques and procedures; modification and/or adjustment of quality control measures..
• Documentation and record keeping of results; graph presentation, statistical analyses and electronic reporting of data.
• Planning and monitoring of resources needed to operate the laboratory in collaboration with the Laboratory Manager; maintenance of inventory control; coordinating of space, equipment and/or facilities use.

Research Assistants conducts multiple experiments on multiple studies in parallel and are responsible for maintenance of equipment used in those experiments.
Qualifications:

• Bachelor's degree in biological sciences or related discipline OR 3 - 6 years of directly related experience in a Laboratory setting.
• Advanced mouse handling and husbandry skills
• Demonstrated ability in execution and development of research protocols
• Demonstrated success in coordinating and/or conducting multiple, concurrent assignments or a multi-faceted project
• Ability to interact with all individuals of a research laboratory in a productive, professional and positive manner
• Established understanding of good safety practices and a demonstrated history of safe conduct
• Self-motivated with the ability to organize time effectively, demonstrated ability to manage details
• Advanced computer skills in Word, Excel and statistical analyses, ability to develop technical documents and presentations
• Demonstrated team player with professional, positive attitude and willingness to be flexible
• Ability to work flexible shifts (evening/week-end/holiday)
• Regular, reliable and consistent attendance
  Research Assistants conducts multiple experiments on multiple studies in parallel and are responsible for maintenance of equipment used in those experiments.
  Requirements for the position:
• Bachelor's degree in biological sciences or related discipline OR 3 - 6 years of directly related experience in a Laboratory setting.
• Advanced mouse handling and husbandry skills
• Demonstrated ability in execution and development of research protocols
• Demonstrated success in coordinating and/or conducting multiple, concurrent assignments or a multi-faceted project
• Ability to interact with all individuals of a research laboratory in a productive, professional and positive manner
• Established understanding of good safety practices and a demonstrated history of safe conduct
• Self-motivated with the ability to organize time effectively, demonstrated ability to manage details
• Advanced computer skills in Word, Excel and statistical analyses, ability to develop technical documents and presentations
• Demonstrated team player with professional, positive attitude and willingness to be flexible
• Ability to work flexible shifts (evening/week-end/holiday)
• Regular, reliable and consistent attendance

About JAX:
The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California), Japan and China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.
Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community. For more information, please visit www.jax.org.
EEO Statement:
The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.