Manufacturing Engineer, ADC - Technical Manufacturing at LOTTE Biologics

We are LOTTE Biologics! A new company, built on 80 years of tradition!

We embody our core values of being Inspired by Science, Embracing Diversity, Fostering Talent, and Connecting Lives. Our mission is to be the most trusted partner in the industry, with high standards of quality and continuous innovation, to reliably deliver benefits for patients worldwide.

We deliver therapies that make a Healthier World!

To help us meet our mission, LOTTE Biologics is in need of a Manufacturing Engineer in ourTechnical Manufacturing department to support facility design, build out, start-up, qualification, and manufacturing processes for Antibody Drug Conjugates (ADCs) and other bioconjugate molecules.  The ideal candidate will have experience with common downstream unit operations such as tangential flow filtration, dead-end filtration, protein chromatography, and conjugation reactions.  This individual will work in a team-driven environment to support facility start-up and transition to GMP manufacturing. This role will be an individual contributor. 

Responsibilities:

• Provide technical input for the continued design and implementation of the facility, equipment, and automated systems.
• Manage and support start-up and commissioning activities (FAT/SAT/IQ/OQ/PQ) including the preparation of test protocols, test execution, troubleshooting, and change control, all per cGMP guidelines.
• As Manufacturing Engineer, you will support operational activities in Downstream of Antibody Drug Conjugate manufacturing, e.g., tech transfer support, material planning, document and batch record preparation, training and troubleshooting, deviation handling.
• Participate on interdisciplinary teams of production personnel, supervisors and specialists and be accountable for the performance and results of assigned projects.
• Guide and support activities for clinical and/or commercial manufacturing in one or more defined DSP areas, e.g., intermediate purification, polishing or drug substance filling.
• Ensure efficient operation of single-use equipment for the purification of therapeutic proteins for the manufacturing of Bioconjugates like Antibody Drug Conjugates (ADCs).

Education/Experience:

• BS or MS degree in Biotechnology, Bio-Chemical Engineering, Biochemistry or related Life Science subject.  Chemical Engineering degree preferred.
• 5+ years of experience as an engineer in the operation, design, construction and/or start-up of biopharmaceutical facilities (cGMP manufacturing plants, pilot plants, laboratories, etc.)
• Work experience with Antibody Drug Conjugates (ADCs) in the biotech/biopharma industry is preferred.
• In-depth knowledge and work experience of downstream processing techniques like chromatography and TFF.

Work Location:

East Syracuse, NY

We believe that women, people of color, veterans and LGBTQ communities must participate in the work we do, so we strongly encourage applications from people with these identities or who are members of underrepresented communities. If this is the work that you want to do in a culture of inclusion and excellence with the goal of making our world to be a healthier place, then please apply today! 

http://www.lottebiologics.com/

LOTTE BIOLOGICS was established in 2022, and is headquartered in Seoul, South Korea. LOTTE BIOLOGICS entered the biologics CDMO business after acquiring Bristol Myers Squibb’s Syracuse biologics drug substance manufacturing site, as of January 1, 2023!

The newly established organization aims to become a Global Top 10 CDMO company in the biopharmaceutical industry.  With initial operations in 1948 in Japan, LOTTE has grown to become the fifth-largest conglomerate corporation in South Korea. LOTTE has various business units, including petro/fine chemicals, food, retail, hotels, electronics, construction, and IT. LOTTE has 30+ global locations across the US, Europe, and Asia.

An Equal Opportunity Employer

We do not discriminate based on race, color, religion, national origin, sex, age, disability, genetic information, or any other status protected by law or regulation. It is our intention that all qualified applicants are given equal opportunity and that selection decisions be based on job-related factors.