LIMS Systems Administrator

Do you want to join one of the fastest-growing molecular diagnostics companies to help transform prenatal and oncology diagnostics that can affect millions of patient lives?

BillionToOne, ranked at the top 5% of Y Combinator companies with $300M+ in funding from prominent VC firms, has developed a DNA molecular counter that increases cfDNA diagnostic resolution by over 1,000x. BillionToOne's first product, UNITY™, is the first and only non-invasive prenatal test that can directly screen an unborn baby and assess its risk for common and severe recessive gene disorders and chromosomal abnormalities, as well as fetal sex and fetal antigens, from a single tube of blood from the pregnant mother without paternal testing.

In 2023, BillionToOne launched two liquid biopsy products that will markedly improve oncology treatment and care. With Northstar Select™, clinicians will be able to select cancer therapies that will be most effective to each patient based on their individual genetic makeup. Northstar Response™ will enable clinicians to monitor a patient's early response to these cancer therapies, by measuring minute changes in their ctDNA, which can reduce ineffective treatments and unwanted toxicity, lower costs, and substantially improve clinical outcomes.

We are looking for a LIMS Systems Administratorto join our growing superstar Process Engineering team in support of clinical patient testing in our high throughput CLIA lab. The LIMS Administrator will be responsible for (1) Evolving the sophistication and usage of BTO's LIMS tools to support rapid scaling of our clinical lab, (2) Identifying and implementing new Quality-oriented changes which enable greater usage, surveillance/monitoring, and control of laboratory data, (3) Managing a relationship with third party developers and our internal engineering team in system integration efforts, and (4) Identifying and assessing new LIMS systems which could offer greater benefits to BTO's larger operations.

This role will help to build upon the strong technology and execution found within BTO's walls, and will help us pave the way for replicating our prenatal success in the oncology space. This is considered an onsite role and will require the majority of days to be spent in the office at either the Menlo Park or Union City sites.

Responsibilities:

• Perform routine LIMS systems and software maintenance procedures
• Collaborate with SMEs to design & implement LIMS workflows & to support new assay launches
• Manage existing LIMS workflows, their operations, lifecycle and data
• Manage full release process, including validation, coordination of training, completion of required documentation, and deployments
• Manage relationships with third party contractors & developers, including running weekly meetings, enforcing deadlines, and tracking contracted hours of work
• Monitor, troubleshooting, and correct systems and software technical issues (e.g. resolving bugs and LIMS outages)
• Triage & escalate unresolved technical issues to appropriate internal teams or external developers
• Network with internal stakeholders & customers to develop new technologies
• Develop and maintain relevant technical documentation (SOPs, Policies, etc) for use of BTO's LIMS systems.
• Ensure compliance to all relevant corporate and regulatory requirements
• Provide end-to-end support & ownership for tickets requiring system change
• Train SMEs across Software Engineering, Data Science, and CLIA to understand LIMS API and data warehouse
• Work with product management teams to maintain and prioritize a backlog of work for information management systems
• Perform periodic review of LIMS performance and report out to senior leadership
• Onboard personnel to LIMS and define systems, roles, and responsibilities
• Set yearly and quarterly goals for Clarity LIMS
• Prioritize and scope features based on goals and timelines
• Define and measure KPIs for Clarity LIMS

Requirements:

• Bachelor's degree in Computer Science, Software or Information Systems or equivalent
• 3-5 Years' Experience with Laboratory Information Systems (LIS)
• 2-4 Years' Experience working in CLIA Lab, medical device, or pharma
• Experience with diagramming workflows using tools such as Lucidchart, Visio, etc.
• Comfortable working with cross-functional teams across CLIA, Supply Chain, Product, Process Engineering, and Software Engineering
• Ability to troubleshoot and diagnose basic technical issues
• Experience with REST APIs
• Experience with Bash
• Experience with Python
• Experience developing scripting solutions to automation problems, especially in a fast paced/agile setting
• Strong attention to detail and ability to work flexibly and well under given timeframes
• Highly organized, strong written and verbal communicator
• Excellent problem-solving and communication skills
• Strong project management skills and familiarity with project management tools such as Jira, Notion, etc.
• Familiarity with Quality Management Systems and related regulations (CFR 21 Part 11, ISO 13485, etc)

Nice-To-Haves:

• Experience with linux environments, including performance monitoring, troubleshooting, and root cause analysis
• Experience with Illumina workflows
• Familiarity with cloud applications (Heroku)
• Experience with Groovy
• Extensive experience with Clarity LIMS
• Direct experience with multiple LIMS products (Clarity, STARLIMS, Labvantage, Labworks, etc)
• Experience with data analysis using Excel, SQL, R, and/or Python

Benefits And Perks:

• Working with a team of 'rockstars' who bring out the best in everyone
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousand patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered at 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Retirement savings program including a 4% Company match
• Free daily on-site lunches provided from top eateries
• Latest and greatest hardware (laptop, lab equipment, facilities)
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses) (2) generous equity options offering, on top of (3) industry leading company benefits (free healthcare options, 401k match, very generous fully paid paternal leave etc.).

For this position, the base pay range is: $130,000-$150,00 per year.