Company

IGM Biosciences, Inc.See more

addressAddressConcord, NC
type Form of workFull-Time
CategorySales/marketing

Job description

About IGM Biosciences, Inc.

IGM Biosciences (Nasdaq:  IGMS ) is a clinical-stage biotechnology company committed to developing and delivering a new class of medicines to treat patients with cancer, infectious diseases, and autoimmune and inflammatory diseases. The Company's pipeline of clinical and preclinical assets is based on the IgM antibody, which has 10 binding sites compared to conventional IgG antibodies with only 2 binding sites. We have created a proprietary IgM antibody technology platform that we believe is particularly well suited for developing T cell engagers, receptor cross-linking agonists, targeted cytokines, and target neutralizers. The Company also has an exclusive worldwide collaboration agreement with Sanofi to create, develop, manufacture, and commercialize IgM antibody agonists against oncology and immunology, and inflammation targets. For more information, please visit  www.igmbio.com .

IgM Antibodies and Autoimmune and Inflammatory Diseases
Antibody treatments have revolutionized outcomes for patients with autoimmune and inflammatory diseases, and IgMs are the first antibody defense against a pathogen infection.  We are committed to exploring how the unique structure and binding properties of our IgM platform can improve outcomes for patients with these serious conditions.

IgM Antibodies and Oncology
IGM Biosciences has a T cell engager program, a receptor cross-linking agonist program and a targeted cytokine program in clinical studies for the treatment of patients with solid tumors and hematological malignancies.  

Position Summary
As the Director, Pharmacokinetics & Biodistribution, you will lead and manage a team for the planning and conduct of preclinical pharmacokinetic and biodistribution studies in multiple species to support our early-stage discovery efforts and IND submissions.
Proven track record of solving complex pharmacokinetic problems and establishing first in human dose and scheduling across multiple therapeutic areas and routes of administration is required. Broad understanding of pharmacokinetics to lead and contribute to improving the general pharmacokinetic attributes of our IgM platform is also required. You will report to the SVP, Preclinical Sciences.  

NOTE: Preference for local or West Coast candidates. Travel of approximately 1+ per month is expected if remote.
Responsibilities:
    • Manage and lead a team of scientists and research associates assessing pharmacokinetics and biodistribution from dedicated preclinical (non-clinical) in vivo PK, pharmacodynamic and efficacy studies
    • Lead strategies for improving the pharmacokinetic and tissue distribution properties of our IgM antibody platform
    • Working cross-functionally to provide pharmacokinetic and pharmacodynamic modeling and simulation, interpretation, and strategic planning for establishing first in human dosing
    • Draft and review reports and sections of regulatory (e.g., IND) submissions
Qualifications:
    • Level commensurate with experience.
    • Ph.D. or equivalent experience in Pharmacokinetics, Pharmaceutical Sciences, Pharmacology, or a related scientific discipline
    • PhD and 10+ years' experience
    • Hands-on experience designing, implementing and analyzing pharmacokinetics and biodistribution studies in multiple species
    • Drafting nonclinical IND reports and sections
    • Proven track record of solving complex pharmacokinetic and bioanalytical problems
    • Experience supervising, training, and motivating teams
    • Excellent interpersonal and collaborative skills, and the ability to work both independently and collaboratively in a highly dynamic environment
    • Must be proficient with software deriving pharmacokinetic parameters (e.g., Phoenix (WinNonLin), R, etc.). 
    • Proficient with basic computer programs routinely used in a lab such as MS Word, Excel, and PowerPoint, and GraphPad Prism
$213,000 - $231,000 a year
The typical annual salary range for this full-time position is $213,000 - $231,000, plus eligibility for cash and equity incentives.

This range reflects the characteristics of the job, such as required skills and qualifications and is based on the office location noted in this job posting. The range may also be adjusted based on applicant's geographic location.

Actual individual pay is determined by demonstrated experience and internal equity alignment.
We offer a fast-paced, collaborative, team-based, work environment. 
 
One of our top priorities is to maintain the health and well-being of our employees and their families. To achieve this goal, we offer comprehensive benefits with a variety of options:
 
         Medical, dental and vision insurance.
         The full premium amount for our employees and their dependents is covered by IGM
         FSA (Flexible Spending Account)
         STD, LTD, Basic Life and AD&D Insurance, Supplemental Life and AD&D Insurance
         401(k) Plan
         120 hours of Paid Time Off, 5 sick days per year, 11 holidays
         Cell phone & internet subsidy
         Employee Referral Bonus Program
         Annual training budget for professional development
         Commuter Benefit
         Annual bonus program
         New hire stock options
 
IGM is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status, and veteran status. All qualified applicants will receive consideration for employment.
Apply for this job
Refer code: 7119284. IGM Biosciences, Inc. - The previous day - 2023-12-16 14:09

IGM Biosciences, Inc.

Concord, NC
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