Company

Cedars-SinaiSee more

addressAddressBeverly Hills, CA
type Form of workFull-Time
CategoryHealthcare

Job description

The Bilsborough Laboratory's Inflammatory Bowel Diseases Drug Discovery and Development is seeking a Biomedical Technician!
The Bilsborough Laboratory's IBD3 unit is composed of research scientists and clinicians with experience in both the biopharmaceutical industry and clinical research.
This position is instrumental in driving our efforts toward developing innovative IBD therapeutics. With a focus on target antibody validation and cell line model generation, this role will help expedite the identification and development of potential drug candidates, streamline our processes, minimize bottlenecks, and ultimately accelerate the progress of our drug development programs.
The Bilsborough Lab's approach is to identify IBD patients with similar types of disease to better understand disease pathology and devise more effective treatments. IBD3 is a unique concept by design, in which an industry-caliber target Discovery and development unit is integrated with an academic research program to accelerate the pace at which scientific findings are brought to bear on patient care. Research in the Bilsborough Lab seeks to personalize drug development and ensure that each patient receives the therapeutic treatment most suited to an individual's disease. In doing so, we seek to accelerate the Drug Discovery process and help put new and effective therapeutic drugs on the market. To learn more, please visit: Bilsborough Research Lab | Cedars-Sinai (cedars-sinai.edu)
Are you ready to be a part of breakthrough research?
The Biomedical Technician participates in projects to develop and achieve compliance with all Federal and State accrediting agency requirements, including Food and Drug Administration (FDA) requirements for good manufacturing practices (GMP) for cellular products. Performs tissue culture and aseptic techniques for developing and processing clinical grade and research grade cellular products in accordance with established standard operating procedures (SOP). Performs process development, validation, and qualification for cellular production in GMP/good laboratory practice (GLP) environment. Responsible for lab maintenance, handling fresh and frozen cellular specimens and products using aseptic techniques, writing and recording controlled documents, and autoclaving for production. Performs all current good manufacturing practice (cGMP) related activities strictly according to SOPs, with accurate documentation, and assists the quality control team with required testing activities. Contributes to the success of projects by providing good documentation, communication skills, and attention to detail. Performs cellular, micro- and molecular biology procedures including Western blot, Northern blot, DNA/RNA, PCR, protein extraction, cell culture, Immunohistochemistry, and staining.
Primary Duties and Responsibilities:
  • Performs a variety of process development tasks for multiple clients following standard operating procedures that will be different for each project based on the type of biomedical work.
  • Writes and maintains good documentation in laboratory notebooks, data records/transfer, SOPs, and batch records.
  • Drafts standard operating procedures and maintains computer database.
  • Verifies samples received, logs samples into systems, and transports to the appropriate environment within the facility for storage following SOPs.
  • Performs lab maintenance duties, including glassware cleaning and sterilization.
  • Maintains lab equipment and related records.
  • Prepares cGMP production room, maintains material inventories, and places orders for equipment and supplies
  • Assists in the operation of specialized equipment and machinery.
  • Ensures all activities comply with regulatory guidelines and safety standards.

Department-Specific Responsibilities:
  • Performing RNA or DNA isolations using commercial kits, glass washing, and autoclaving, making media and bacterial culture plates, data analysis using Excel or GraphPad Prism.
  • Preparation of graphs and creating PowerPoint slides to present data to others, attending lab and department meetings, researching (NCBI/PubMed), and understanding experimental particulars in the scientific literature as necessary to supplement training.

Education:
  • Associate's Degree in Molecular Biology, Biochemistry, or related science/engineering field is required. Bachelor's Degree is preferred.

Experience and Skills:
  • One (1) year of experience working in a lab or biotech environment is required.
  • Tissue culture experience (aseptic technique); molecular biology (PCR or molecular cloning) experience required, protein or DNA gel electrophoresis experience preferred but can be trained.
  • Experience in ELISA, western blotting, or immunofluorescence preferred.
  • Familiarization with CRISPR technology is a plus.
  • Collaborates to problem solve and make decisions to achieve desired outcomes.
  • Responds timely, effectively, and appropriately to deliverables.
  • Establishes effective working relationships with cross-functional team(s).
Refer code: 6633458. Cedars-Sinai - The previous day - 2023-12-02 23:50

Cedars-Sinai

Beverly Hills, CA
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