Associate Director / Director, Discovery Immunology

Company Overview:

Vividion is a next generation biotechnology company based in San Diego that is leveraging its proprietary chemical proteomics platform to conduct proteome-wide footprinting of drug-protein interactions with unprecedented breadth and precision. Our technology allows us to screen, identify and optimize novel drugs that selectively bind virtually any protein, including proteins previously considered “undruggable”. Our pipeline and emerging programs reflect a matured and productive platform capable of delivering first in class drugs utilizing novel mechanisms of action (allosteric inhibitors, protein-protein interaction inhibitors, functional activators, degraders etc.) against undruggable targets in the oncology and immunology space.

We prize scientific excellence, creativity, team players and we are committed to continued innovation. We have worked hard to create a collaborative and dynamic work culture where your ideas and discoveries are valued and will have an impact. We are growing and there are opportunities for mentorship and career progression.

Vividion was ranked #2 mid-size company on The San Diego Union-Tribune's 2023 Top Workplaces list.

Job Summary:

We are seeking a highly motivated, experienced scientist to join our expanding Immunology team to support the expanding portfolio of small molecules targeting autoimmune & inflammatory diseases. This individual will report to the Head of Immunology and will be responsible for leading efforts to identify targets, strategy for target validation and discovery efforts for advancement into lead optimization stage. The individual will help prioritize immunology programs while establishing decision-making cascades, aligning go/no-go milestones, timelines and resourcing required for program success. The ideal candidate will have broad scientific experience with demonstrated expertise in target validation of novel targets for immunology and autoimmune diseases.

Essential Duties and responsibilities:

• Lead a team of scientists focused on target proposal, validation, and progression through lead optimization.
• Deep expertise in Immunology and experience developing workflows for assay development and implementation of cutting edge-technologies for target validation.
• An understanding of HTS principles would be beneficial.
• Expert knowledge of adaptive and innate immunity, including the roles of various immune cells, and key pathways implicating in immune regulation and autoimmune diseases (I&I), and working knowledge of computational biology approaches to identify target to disease relationships.
• Provide mentorship and development of colleagues and reports in the group.
• Partner closely with the leadership team to drive and support the strategic direction of the company’s platform towards identifying and validating targets in autoimmunity (I&I) and present these to external as well as internal stakeholders.
• Closely interface with program co-leads and leadership teams to align with program strategy, timelines, company goals and deliverables.

Experience and education requirements:

• Ph.D. in immunology, cell biology, and/or autoimmune diseases with 7-10 years of relevant industry experience
• Expert knowledge of adaptive and innate immunity and understanding of biological principles underpinning immunological diseases
• Experience in designing the workflow for validating discovery targets and experience in setting up the relevant in vitro and in vivo model systems in autoimmune and/or inflammatory disease.
• Track record in advancement of therapeutics in autoimmune/inflammatory disease

Pay & Benefits:

The annual base salary for this position ranges from $175,000 to $210,000 depending on relevant skills, experience, and education. In addition, this position is eligible for target bonus, long-term-incentives, 401k retirement savings plan with company match, and a comprehensive benefits package which includes medical, dental, vision, life, and disability insurance. Relocation assistance may be available based on business needs and/or eligibility.

EEO & Employment Eligibility:

Vividion Therapeutics, Inc. is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Privacy Policy:

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