Address
Form of work2024 Summer Internship - Biology Research | AI Development
BRAID (Biology Research | AI Development) Department within Genentech Computational Biology and Translation (CBT) focuses on developing and applying novel machine learning methods to impact biological discovery with the ultimate goal of impacting drug discovery and human health. We work collaboratively across disciplines both within the divisions and also with collaborating labs in Research Biology.
As part of a collaboration between the departments of BRAID and Bioinformatics within CBT, we are searching for a motivated summer intern to work on designing, developing, interpreting and visualizing ML models of regulatory DNA to improve our understanding of gene regulation, predictions of common disease variants and genome engineering. The candidate will work as part of a team of summer interns furthering our sequence modeling approaches that can be used to advance programs in gene and cell therapy.
This internship is located on-site in South San Francisco, CA
Key responsibilities
Required education
Required skills
Other Preferred Qualifications
The expected salary range for this position based on the primary location of San Francisco, CA is $30 - 50/hr. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for paid holiday time off benefits.
Relocation benefits are not available for this job posting.
#GNE-gCS-2024-Interns
Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status.
BRAID (Biology Research | AI Development) Department within Genentech Computational Biology and Translation (CBT) focuses on developing and applying novel machine learning methods to impact biological discovery with the ultimate goal of impacting drug discovery and human health. We work collaboratively across disciplines both within the divisions and also with collaborating labs in Research Biology.
As part of a collaboration between the departments of BRAID and Bioinformatics within CBT, we are searching for a motivated summer intern to work on designing, developing, interpreting and visualizing ML models of regulatory DNA to improve our understanding of gene regulation, predictions of common disease variants and genome engineering. The candidate will work as part of a team of summer interns furthering our sequence modeling approaches that can be used to advance programs in gene and cell therapy.
This internship is located on-site in South San Francisco, CA
Key responsibilities
- Work directly with research software engineers to develop functional genomics visualization methods compatible with ML models of regulatory sequence
- Train/finetune regulatory models on disease relevant genomics data (single-cell ATAC-seq, MPRA, ChIP-seq)
- Contextualize and predict the impact of edits in the genome sequence using ML models
Required education
- Pursuing an undergraduate degree or PhD in Bioengineering, Computer Science or Engineering, Data Science or related fields
- Will have completed at least two years of undergraduate coursework at an accredited college/university.
Required skills
- Proficiency in Python and experience with frameworks for machine learning inference (e.g. Pytorch, TensorFlow, Lightning)
- Familiarity with fundamental ML concepts and interpretation techniques such as transformers, saliency maps, DeepLIFT/DeepSHAP
- Experience with popular regulatory genomics models such as Borzoi, Enformer and BPnet as well as DNA language models,,
- Previous educational exposure to basic concepts in cell biology and gene expression
Other Preferred Qualifications
- Excellent communication, collaboration, and interpersonal skills.
- Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion.
The expected salary range for this position based on the primary location of San Francisco, CA is $30 - 50/hr. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for paid holiday time off benefits.
Relocation benefits are not available for this job posting.
#GNE-gCS-2024-Interns
Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status.
