Senior Scientist, Oligonucleotide Chemistry - Analytical

Janssen Research & Development, LLC, a member of Johnson & Johnson's Family of Companies, is recruiting for a Senior Scientist, Oligonucleotide Chemistry - Analytical in the RNA, Gene Therapy & Delivery organization, located in La Jolla, CA.

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/.

RNA, Gene Therapy & Delivery is an organization within Therapeutics Discovery, committed to the delivery of high-quality drug candidates in the novel synthetic modalities space working closely with Johnson & Johnson Innovative Medicines Therapeutic Areas (TA) discovery teams. Our mission requires critical thinking, a portfolio approach and deep scientific expertise in several fields including Oligonucleotide Chemistry, bioconjugation chemistry, nanotechnology, cellular and molecular pharmacology and screening technologies coupled with an ability to work collaboratively with internal and external partners. This role offers tremendous growth opportunity within a dynamic and science driven organization.

Key Responsibilities:

• Lead analytical characterization efforts of oligonucleotides and bioconjugates
• Establish robust standardized and novel analytical methodologies to support oligonucleotide innovation, optimization and process development efforts
• Support the analytical characterization needs of the team for solid phase synthesis and purification of oligonucleotides and bioconjugates
• Critically evaluate experiment data and communicate scientific findings as verbal presentations and written reports

Qualifications

• Ph.D. in organic/medicinal chemistry, chemical biology, or related field with more than 5 years of industry experience in oligonucleotide drug discovery
• Significant experience in analytical chemistry and related instrumentation, especially related to root-cause analysis investigations
• Ability to work on complex issues with a deep technical understanding of reagent chemistry and related instrumentation
• Excellent critical thinking and scientific skills and a demonstrated ability to interpret and clearly communicate complex data
• Strong team player with the ability to work effectively in a dynamic matrix team environment with diverse views
• Ability to adapt to changing priorities and timelines

Preferred Qualifications:

• Postdoctoral experience with an emphasis on nucleic acid chemistry

• Proven track record of accomplishments in oligonucleotide research in the form of patents, publications and/or presentations at major national meetings

• Working knowledge and experience of oligonucleotide and bioconjugate synthesis
  

The anticipated base pay range for this position is $113,000 to $195,500.

The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation’s performance over a calendar/performance year. Bonuses are awarded at the Company’s discretion on an individual basis.

Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.

Employees may be eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k).

Employees are eligible for the following time off benefits:

• Vacation – up to 120 hours per calendar year.
• Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington – up to 56 hours per calendar year.
• Holiday pay, including Floating Holidays – up to 13 days per calendar year.
• Work, Personal and Family Time - up to 40 hours per calendar year.

Additional information can be found through the link below.

For additional general information on Company benefits, please go to: https://www.careers.jnj.com/employee-benefits .

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

For more information on how we support the whole health of our employees throughout their wellness, career and life journey, please visit www.careers.jnj.com .