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Form of workAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.
Scientist/Sr. Scientist (Advisor/Sr. Advisor), mRNA
Highly motivated and creative scientist that will help build the company’s mRNA technology exploration and production platform. The successful candidate will support R&D efforts within the company, initially as an individual contributor and in the future as a small team lead, focused on research-grade mRNA production and exploration of therapeutic mRNA optimization strategies. A deep technical background in mRNA technology and design, experience working with several mRNA modalities are required. Strong organizational and communication skills, creative problem-solving, and flexibility are essential.
Job responsibilities:- Lead projects to develop, design, construct, and evaluate mRNA therapeutics.
- Design and perform routine molecular biology experiments, including mRNA design, molecular cloning, in vitro transcription, etc.
- Establish cell-based assays to evaluate mRNA activity and expression of therapeutic proteins and antigens.
- Contribute to projects directly at the bench and later by leading one or more Research Associates.
- Clearly communicate results and recommendations to collaborators, colleagues, managers, and senior management, leading project decision-making.
- Contribute to the company’s intellectual property portfolio by generating new ideas, recommending technical strategy, reading broadly in relevant fields, and diligently maintaining organized records.
- Ph.D. in Molecular Biology, Biochemistry, Cell Biology, or related discipline with 2+ years of relevant academic or pharmaceutical industry experience (can include post-doc experience), or a Master's degree with 10+ years of experience.
- Deep understanding of applications and technical challenges with more than 1 mRNA therapeutic modality (mRNA, saRNA, circRNA, etc.).
- Experience with therapeutic mRNA clone design and proficiency with molecular design software tools (SnapGene, Geneious, or equivalent).
- Experience with mRNA IVT and purification.
- Experience with characterization of DNA/RNA molecules using state-of-the-art techniques.
- Experience with cell-based mRNA activity assay development.
- Strong organization, communication, and interpersonal skills, with the ability to drive projects in a highly collaborative work environment.
- Relevant publication record in academic and/or patent literature.
- Familiarity with emerging mRNA technologies and understanding of industry trends.
- Familiarity with high-throughput assays and/or processes development
- Exposure to preclinical development of mRNA therapeutics.
- Enthusiasm about lab automation and incorporation of automated liquid handlers in lab workflows.
- Familiarity with Scrum or other Agile framework
Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( Lilly_Recruiting_Compliance@lists.lilly.com ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.
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Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.
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