Scientist - Rna Therapeutic Discovery

About Ascidian:
Ascidian is redefining the treatment of disease by rewriting RNA.
Ascidian Therapeutics was founded to rewrite RNA by editing and replacing human exons. We were inspired by ocean creatures, called Ascidians, who are primordial ancestors of vertebrates. To grow from larvae to adults, ascidians re-engineer their transcriptome through RNA editing via trans-splicing and alternative splicing.
In our Brighton/Boston labs, RNA biology meets today’s cutting-edge genomics, computational biology, and deep-sequencing technologies to create a new class of medicines that address the underlying causes of disease.
We welcome you to come join our vibrant team and help us lead the way into a new gene therapy era.
YOUR ROLE ON THE TEAM

We are seeking a Scientist with molecular biology experience to join the RNA Therapeutic Discovery Team. The successful candidate will work both independently and as part of a team to design and test novel RNA therapeutics. The successful candidate will be creative, detail oriented, have excellent communication skills, and be willing to work in a dynamic environment. A commitment to the collective success of the team is essential.

 
JOB RESPONSIBILITIES

• Design, execute, and interpret experiments to improve therapeutic performance of designer RNA molecules
• Support the creation and expansion of the company’s intellectual property
• Interpret data, generate figures, and clearly communicate findings to the team
• Maintain detailed records using ELN

SKILLS/CAPABILITIES

• Proficiency with basic molecular biology techniques: plasmid design, cloning, primer design and PCR, DNA isolation, gel electrophoresis, Sanger sequencing analysis
• Proficiency with RNA extraction and quantification by qPCR
• Protein extraction and western blot
• Cell culture and transfection
• Eagerness to learn and receptive to feedback
• Demonstrated problem solving and trouble-shooting skills 

REQUIRED EDUCATION/EXPERIENCE

• PhD in molecular/cellular biology, biochemistry, genetics, or related field with 5+ years relevant laboratory experience
• Background in RNA, muscle biology, and/or neuroscience preferred

A final note - we highly encourage you to apply for our position, even if you are not sure you meet all the requirements. Everyone has unique talents, and at Ascidian, we look not only at your experience but your potential. We know that the best teams consist of diverse backgrounds, so please apply!