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Form of workWho we are.
Dendreon is making the battle against cancer personal. Our flagship product PROVENGE® (sipuleucel-T), was the first FDA approved immunotherapy for the treatment of metastatic castrate resistant prostate cancer and is made from the patient's own immune cells.
If you are looking to positively impact the lives of patients, we want you to join our team. We have Immunotherapy Manufacturing Facilities located in Seal Beal, CA and Union City, GA. A sizeable Research & Development group based out of Seattle, WA, and a highly skilled Commercial team countrywide.
Core Values:
- Put Patients First. Every day is a new opportunity to improve the lives of patients living with cancer.
- Act with Integrity. Be honest, transparent, and committed to doing what’s right in every situation.
- Build Trust. Building trust takes time. Engage teammates, be candid and transparent. Over communicate and seek feedback.
- Raise the Bar. Harness continuous improvement, foster innovation and elevate our people.
- Drive Results. Be accountable and execute – we win together when everyone performs
Your Role:
The Scientist will develop assays from different platforms with focus on flow cytometry. The Scientist Is also involved in the execution of immune cellular monitoring and characterization experiments in support of Dendreon’s Autologous Cellular Immunotherapy (ACI) platform.
Your Work:
- Perform Assay Development from different platforms (ranging from cell-based assay to flow cytometry)
- Process blood from clinical trial subjects to generate samples for immune monitoring.
- Perform cellular and humoral assays to monitor immune responses of PBMC from clinical trial samples.
- Perform product characterization assays including, but not limited to, multi-color flow cytometry and multi-analyte cytokine analyses.
- Analyze results using multi-factor modeling and statistical analysis.
- Document results and outcomes in technical reports.
- Maintain a high level of professional expertise through familiarity with scientific literature.
- Support the management of Clinical Immunology laboratory, including inventory control, equipment maintenance, supply management and general care for the laboratory environment.
- Maintain laboratory notebooks, experimental records as well as computer files and databases.
- Represent Clinical Immunology in cross-functional team meetings, present results and conclusions.
- Work independently and demonstrate ability of mentorship.
Scope:
- Uses professional concepts, company policies and procedures to solve a variety of problems.
- Works on problems of complex scope.
- Works with supervision on complex tasks.
- Works with a high level of independence on complexity tasks.
Job Requirements:
- M.S. with 2-5 years experience preferred, or B.S. with 8-10 years proven expertise and appropriate experience in the field of cell biology and or cellular immunology.
- Expertise in Assay Development
- Expertise in flow cytometry
- Expertise in bioassay analytical techniques including, cell culture, ELISA, cell based assays.
- Familiar with cell free DNA technology a plus
- Familiarity with cGMP requirements.
- Ability to solve problems through analysis.
- Excellent written and verbal communication skills.
- Strong organizational skills required.
- Proficient in MS Office applications.
Working Conditions and Physical Requirements:
- Light lifting will be required.
- Ability to safely handle potentially hazardous materials.
- Requires occasional evening and weekend work.
