Scientist, Computational Bio Analyst- Immunology Translational Science & Medicine

Johnson & Johnson Innovative Medicine, a member of Johnson and Johnson's Family of Companies, is recruiting for a Computational Scientist, Translational Science (TS), Immunology Translational Science and Medicine (TSM) to be located in La Jolla, CA. At the Johnson & Johnson Innovative Medicine, what matters most is helping people live full and healthy lives. We focus on treating, curing and preventing some of the most devastating and complex diseases of our time. And we pursue the most promising science, wherever it might be found.

Johnson & Johnson Innovative Medicine discovers and develops innovative medical solutions to address important unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, and cardiovascular and metabolic diseases. Please visit http://www.JanssenRnD.com for more information.

We are Johnson & Johnson Innovative Medicine. Our mission drives us. Our patients inspire us. We collaborate with the world for the health of everyone in it. Thriving on a diverse company culture, celebrating the uniqueness of our employees and committed to inclusion. Proud to be an equal opportunity employer.

Johnson & Johnson Innovative Medicine Immunology has a history of bringing life-changing therapies to patients with immune-mediated diseases. Translational Science and Medicine (TSM) is an integrated group of scientists composed of a clinical Translational Medicine (TM) team which conducts early clinical development and experimental medicine studies, and a Translational Science (TS) team which uses human disease data to support the portfolio from early development to late stage clinical assets. Together, the TSM group provides the key learnings/insights on the next wave of novel therapies for patients. Organizationally, TSM serves as a pivotal bridge between Discovery Research and the later phase Clinical Development group. TSM provides the necessary scientific and clinical expertise to advance an industry-leading pipeline of novel mechanism small molecules and biologic agents to address unmet need in immune-mediated diseases.

TS has a broad remit stretching from support of discovery with human data to support target selection, through development of novel decision- making biomarkers for early phase clinical trials, target-centric indication sequencing and prioritization, and biomarker support of regulatory filings. TS has expertise in biomarker development, disease biology research and in the application of immunology and data science technologies to support drug discovery and development.

This is a position within the Translational Immunomics group of TSM. The group is responsible for delivering analysis of 'omics datasets (e.g. genetics, gene expression, proteomics) to support portfolio projects within the Immunology Therapeutic Area. The successful candidate will contribute to the Computational Biology and genomics strategy for Immunology programs and will be effective in the use of relevant computational tools to deliver analysis and interpretation of high-dimensional biological data across all aspects of portfolio development.

The Scientist will serve as a Computational Biology analyst in the immuno-dermatology area and will be accountable for analytical and platform support for drug development programs as well as providing strategic input to TSM colleagues. The candidate will bring an enthusiastic, rigorous and enterprise thinking mindset to Translational Immunomics team.

Responsibilities are as follows:

• Effectively use relevant computational tools to deliver analyses of high-dimensional biological ('omics) data to support all aspects of portfolio development in immuno-dermatology
• Design and execution of data analysis, interpretation of results, documentation and generation of analysis reports
• Ensure delivery of completed data and analyses in support of key program milestones and drive technical excellence in Translational Science and biomarker research
• Contribute to the strategies enabling molecular understanding of immune driven human diseases, patient stratification and generation of biomarker-based endpoint
• Lead projects with internal groups/external collaborator
• Communicate analysis results to key stakeholders

• PhD degree in Bioinformatics, Computational Biology, Immunology or related field, with 3 years relevant experience is required.

• Documented experience and proficiency in analysis of NGS transcriptomics (single cell and bulk RNAseq) and proteomics datasets is required.

• Proficiency in programming with R, Python, or similar language for 'omics analysis is required

• Expertise in multimodal data integration is preferred.

• Industry and/or translational research experience is highly preferred.

• Experience working within cross-function teams is preferred.

• Outstanding communication and collaboration skills are required.

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

IMPACTIMM