AddressHOW MIGHT YOU DEFY IMAGINATION?
You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.
Process Development Senior Scientist – HTE Solid State / Crystallization
(Synthetics)
Live
What you will do
Let’s do this. Let’s change the world. Amgen is currently seeking a dedicated Process Development Senior Scientist to join our High-Throughput Experimentation (HTE) & Automation group in Drug Substance Technologies – Synthetics (DSTS) at Thousand Oaks, CA. Amgen’s DSTS group within Process Development (PD) organization is responsible for the invention and development of drug substance manufacturing processes and technologies to advance Amgen's exciting portfolio of synthetic and hybrid assets. Process chemists/chemical engineers within the HTE & Automation group support high throughput screening activities, including polymorph screening, salt screening, solubility measurements and solid-state characterization, and assist drug substance teams with the development of robust crystallization processes. The successful candidate will be a highly motivated and team-oriented individual with a strong background in chemical engineering and/or chemistry with a consistent track record of scientific innovation and achievement.
Scientific/Technical Responsibilities
Design and perform high-throughput polymorph screening, salt screening, solubility measurements and solid-state characterization of drug substance intermediates.
Develop crystallization processes for active pharmaceutical ingredients (API) and drug substance intermediates that optimize quality, physical properties, morphology and particle size distribution.
Support cGMP manufacturing and technology transfer to our internal manufacturing facilities and external contract manufacturers.
Advance digital and automation technology to support high-throughput workflows and enhanced crystallization development.
Serve as a technical expert and keep current in the field of solid form science and crystallization engineering.
Actively contribute to drug substance development teams by providing project updates, data interpretation, and technical recommendations.
Maintain good laboratory documentation practices and compliance with electronic laboratory notebook (ELN) guidelines.
Work effectively in a multi-disciplinary team of chemists, engineers and attribute scientists.
Work independently in advancing projects and studies within required deadlines.
Win
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The scientific professional we seek will possess these qualifications.
Basic Qualifications:
Doctorate degree PhD OR PharmD OR MD in Chemical Engineering or Chemistry completed by June 2024
Or
Master’s degree in Chemical Engineering or Chemistry and 3 years of industry experience
Or
Bachelor’s degree in Chemical Engineering or Chemistry and 5 years of industry experience
Preferred Qualifications:
Ph.D in chemical engineering with a specialization in solid form science and/or crystallization engineering
Demonstrated ability to conduct independent research
Experience in solid‐state techniques (DSC, TGA, XRD, PLM, DVS, particle characterization, Raman, IR, etc.)
Experience with automation systems (e.g., Unchained Labs, Chemspeed, Chronect, etc.) and data visualization software (e.g., Spotfire)
Excellent communication skills (both written and oral) and the ability to work well in teams
Thrive
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.
Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:
Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans and bi-annual company-wide shutdowns
Flexible work models, including remote work arrangements, where possible
Apply now
for a career that defies imagination
Objects in your future are closer than they appear. Join us.
careers.amgen.com
Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
