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Form of workJanssen Research & Development, LLC, a member of Johnson & Johnson's Family of Companies, is recruiting for a Principal Scientist, AAV and RNA Process Development located in San Diego, CA.
At Johnson & Johnson,we believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented, treated, and cured,where treatments are smarter and less invasive, andsolutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/.
Specifically, you will lead manufacturing and investigations supporting early phase products. You will be responsible for designing and performing laboratory analyses of manufacturing process and investigations and summarizing findings in reports. You will also coordinate and lead all aspects of technical capabilities in the laboratory, ensuring calibration, maintenance and compliance for equipment that supports our key initiatives. You will support experiments for the evaluation and implementation of new technologies (including DoE design, technology scouting, analytical testing) working closely with various partners including discovery, engineering and site technical operations. As part of an international and multidisciplinary team, you will provide summaries of data generated for project updates and founded proposals for decisions and coordinate the planning of activities in close interaction with management.
Principal Responsibilities:
• Working closely with Therapeutics Discovery and the manufacturing site, develop robust, scalable, and well characterized unit operations for USP and DSP procedures for AAV vectors or short and long RNA molecules.
• Design, complete and analyze experiments for existing and novel methods, processes, and equipment technologies.
• Collaborate with multi-functional teams to collect data and advise experimental design.
• Maintain detailed documentation through electronic lab notebooks, technical reports, and technical presentations.
• Communicate findings to a wide audience in a timely and clear fashion.
• Leads continuous improvement for methods, processes and/or scientific procedures.
• Proactively investigates, proposes, and develops improvements to existing processes or develops new processes.
• Maintain positive relationships with internal and external partners to facilitate teamwork across functions.
• Deliver reproducible and impactful results under ambitious timelines.
• Work at a high level of autonomy, develop manufacturing processes of early assets.• A minimum of a Bachelor's degree in Biochemistry, Engineering, Virology, Chemistry or related scientific field is required with at least 15 years of meaningful experience; or at least 10 years of relevant experience with a Master's degree; or 6 years of relevant experience with a PhD degree is required.
• Direct Process Development experience with viral vectors or RNA molecules is required.
• Experience with chromatography and TFF instrumentation is required.
• Ability to independently design, complete and troubleshoot experiments, analyze, report and present data is required.
• People leadership experience, working in a matrix team or direct line setting, is a plus.
• Experience with proven record of scientific achievement associated with the implementation of innovative process technologies is preferred.
• Experience writing and reviewing technical documents and familiarity with statistical methodology such as DOEs is preferred.
• Experience in maintaining team-based Collaborations is required.
• Must have excellent oral and written communication and presentation skills.
• Must have strong problem-solving skills.
• Must be highly organized and capable of managing/pursuing multiple projects independently.
The anticipated base pay range for this position is $135,000 to $232,300.
The Company maintains highly competitive, performance-based compensation programs. Under
current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation's performance over a calendar/performance year. Bonuses are awarded at the Company's discretion on an individual basis.
Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.
Employees may be eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k).
Employees are eligible for the following time off benefits:
- Vacation - up to 120 hours per calendar year.
- Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington - up to 56 hours per calendar year.
- Holiday pay, including Floating Holidays - up to 13 days per calendar year.
- Work, Personal and Family Time - up to 40 hours per calendar year.
Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
