AddressHOW MIGHT YOU DEFY IMAGINATION?
If you feel like you’re part of something bigger, it’s because you are. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies. We are global collaborators who achieve together—researching, manufacturing, and delivering ever-better products that reach over 10 million patients worldwide. It’s time for a career you can be proud of.
Principal Data Scientist - Bioinformatics Technologies
Live
What you will do
Let’s do this. Let’s change the world. In this vital role you will join the Bioinformatics Technologies team within Amgen’s Center for Research Acceleration by Digital Innovation (CRADI). CRADI is a multi-disciplinary effort embedded within our drug discovery engine that continually uses advancement in digital technologies for disease modeling and digital modality engineering to accelerate our pipeline from target inception through drug development. This pivotal role within CRADI’s Computational Biology and Bioinformatics platform will assist in establishing an innovation engine for deploying and exploiting emerging digital technologies in the field of computational biology.
In this role you will set strategy, develop, and implement computational models on multi-modal, multi-omics data to accelerate the execution of strategic imperatives for preclinical biomarker discovery. Work collaboratively with scientists within preclinical research and clinical biomarkers as well as Data Scientists and engineering partners across Amgen R&D. An ability to communicate clearly and collaborate effectively with colleagues from different fields will be essential.
Design, execute, interpret, and report on multi-dimensional studies using bulk, single-cell, and spatial omics technologies that will expedite the pace of research biomarker discovery and translation in early drug discovery across therapeutic areas
Find opportunities and set strategy for digital innovation in the field of computational biology
Initiate and lead the development of advanced quantitative methods, such as topological data analysis, causal inference, discriminative, and generative AI/ML, to push the state of the art in integrative omics-based biomarker detection
Collaborate with engineers, Data Scientists, and research scientists to develop innovative bioinformatics tools and cloud-native workflows that facilitate data access, model utilization, and output interpretation
Serve as subject matter expert for multi-modal single-cell and spatial omics technologies
Mentor junior Data Scientists and engineers, providing technical guidance within a formal or matrix structure
Advise stakeholders on omics data generation, analysis, and interpretation
Translate findings into computational model design and refinement
Document methods and analyses to ensure reproducible research
Communicate project results and data-driven recommendations to collaborators and cross-functional partners
Monitor, review, and critically interpret published computational research in the field of computational biology and bioinformatics
Win
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a scientist with these qualifications.
Basic Qualifications:
Doctorate degree
Or
Master’s degree and 6 years of computational biology, bioinformatics, biomedical data science or related field
Or
Bachelor’s degree and 8 years of computational biology, bioinformatics, biomedical data science or related field
Preferred Qualifications:
PhD in computer science, data science, computational biology or bioinformatics
Extensive experience and a deep theoretical understanding of statistical modeling, machine learning, deep learning, causal learning, topological data analysis, and other relevant quantitative methods
Proven record of innovative thinking to propose and champion the development of novel algorithms and AI/ML models that generated interpretable and actionable results for biomarker discovery
Solid knowledge in molecular biology and genetics
Comprehensive understanding of drug discovery and development process
Skilled in integrative analysis of omics data, including single-cell and spatial sequencing data
Proficient in systems biology, such as in silico modeling of cellular response to drug or genetic perturbations
Fluency in scientific programming and tool development with R, Python, or equivalents
Familiarity with Dev/MLOps and software best practices, such as version control, continuous integration, test driven development
Experienced in cloud computing
Creative and open-minded, with a passion for scientific research
Exceptional analytical skills, capable of collecting, organizing, analyzing, and disseminating significant amounts of information with attention to detail and accuracy
Demonstrated ability to thrive in a team environment
Strong interpersonal, collaborative, organizational, and presentation skills
Excellent communication skills, both written and verbal
Thrive
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:
Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans and bi-annual company-wide shutdowns
Flexible work models, including remote work arrangements, where possible
Apply now
for a career that defies imagination
Objects in your future are closer than they appear. Join us.
careers.amgen.com
Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
