Neuromuscular Intern, Gene Editing

The Intern has strong laboratory training and expertise and performs in vitro, ex vivo, and/or in vivo studies to investigate the effects of CRISPR-based Gene Editing on gene and protein expression, tissue pathology, and disease phenotype in animal models of neuromuscular disorders. This role provides laboratory support of day-to-day GCLP analyses and develops cutting-edge CRISPR-based technology platforms for research and therapeutic applications.
Primary Responsibilities Include:

• Plans and conducts experiments at the direction of scientists, performs routine laboratory functions using a variety of assay formats such as molecular cloning, nucleic acid and protein purification, Western blot, PCR, next-generation sequencing, and histological analyses, and coordinates activities and timelines through close collaboration with the laboratory head and other laboratory staff.
• Participates in evaluation and implementation of new technologies to improve quality and robustness of sample analysis.
• Troubleshoots routine technical challenges and contributes to their resolution.
• Contributes to safe, efficient and effective laboratory environment with personal accountability; equipment procurement and maintenance, lab set up and maintenance; ordering of reagents, glass and plastic-ware kits and equipment to keep the laboratory stocked and functional.
• Maintains compliant laboratory records, authors technical documents, protocols and reports; ensures effective high quality timely and appropriate documentation in laboratory notebooks and internal technical reports in accordance with Good Documentation Practices (GDPs).
• Performs other related duties as assigned.

Desired Education and Skills:

• In a Master's or PhD program, or has completed B.S. degree in Biochemistry, Immunology, Cell Biology, Bioengineering, or related field with at least 1 year of relevant experience in a laboratory setting.
• Demonstrated mastery of basic laboratory methods working with attention to detail and high standards for data integrity and quality.
• Proven experience with a variety of analytical techniques, methods of development and validation.
• Ability to execute sample handing, testing, data management and data analysis with strict adherence to Good Laboratory Practices and SOPs.
• Knowledge of protein quantitation, SDS-PAGE, Western blot. Experience with gene expression analysis and PCR.
• Desire to work in a high-functioning, collaborative team.
• Experience with computer productivity software (i.e. Word, Excel, etc.).
• Excellent written and verbal communication skills.
• Desire to work in a dynamic, fast-paced team environment and to make a difference in the lives of people through our innovative medicines.

Program Timeline:

• This application is for a 10 or 12-week summer internship program that will either start on May 28th or June 10th.
• The program will conclude on August 16th, 2024.

This is a facility-dependent position where in-office presence is required four-five days a week.
#LI-Onsite
This position requires work on site at one of Sarepta's facilities in the United States.
The targeted salary range for this position is $21 - $25 per hour depending upon years of education completed and nature of role.
Candidates must be authorized to work in the U.S.
Sarepta Therapeutics offers a competitive compensation and benefit package.
Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.