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Form of workAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
The Diabetes, Obesity and Complications Therapeutic Area (DOCTA) focuses on the discovery of biological, small molecule and genetic therapeutics for the treatment of diabetes, obesity and associated complications. We are seeking a skilled and motivated in vitro biologist to be part of a highly collaborative, successful drug discovery and development team in the Dyslipidemia and New Modality research group in Indianapolis. The successful candidate will use their strong molecular/cellular biology laboratory skills to play a critical role in initiating discovery efforts and supporting established pipeline projects with an emphasis on therapeutics targeting obesity, metabolic disease, and dyslipidemia. You will also establish critical capabilities in the laboratory setting as well as working with other scientists within and across departments to achieve project and department goals.
Are you proficient in a wide array of cell biology techniques including cell culture, transfection, FACS and other cell-based assays? If so, apply today to join the Lilly Team!
Key responsibilities include:
- Plan and independently implement in vitro and cell-based experiments to support preclinical characterization and evaluation of relevant targets and pathways using CRISPR technologies.
- Perform molecular and biochemical assessments on samples from tissues and cells including RNA/DNA isolation and analysis, gene and protein expression analyses, and other analytical techniques.
- Be adaptable, showing the ability to establish new techniques, learn new biology, and quickly pivot in a data-driven environment.
Minimum qualifications:
- BS in biology or related field
- 5+ years of proven experience in cellular and molecular biology and in vitro assay development in the pharmaceutical industry
Additional Skills/Preferences
- A background in biology, cell/molecular biology, and metabolic disease
- Knowledge/hands-on experience in implementation of gene editing methods and analysis including gDNA/RNA isolation, sequencing (Sanger, NGS, long-read), gene expression (qPCR), ddPCR, and protein expression (western, JESS, ELISA, MSD).
- In-depth mechanistic understanding of CRISPR/Cas systems
- Experience with computational/bioinformatics tools used for NGS analysis
- Experience with complex cell culture systems, primary culture, co-culture, and stable cell line generation
- Experience with various assay detection technologies (fluorescence, luminescence, FRET, alpha-screen, radiometric assays) while also implementing and validating new technologies
- Support the implementation of new assay technologies
Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively "Lilly") are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( Lilly_Recruiting_Compliance@lists.lilly.com ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.
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